Could the tumor-associated microbiota be the new multi-faceted player in the tumor microenvironment?

Frontiers in Oncology

Oncology

Anne-Gaëlle Goubet¹ 

[1] Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland;AGORA Cancer Research Center, Lausanne, Switzerland;Swiss Cancer Center Léman, Lausanne, Switzerland;

关键词: microbiome;    microbiota;    cancer;    tumor;    tumor microenvironment;    tumorassociated microbiota (6);   

DOI  :  10.3389/fonc.2023.1185163

 received in 2023-03-13, accepted in 2023-05-02,  发布年份 2023

来源: Frontiers

【 摘 要 】

Microorganisms have been identified in tumor specimens for over a century. It is only in recent years that tumor-associated microbiota has become a rapidly expanding field. Assessment techniques encompass methods at the frontiers of molecular biology, microbiology, and histology, requiring a transdisciplinary process to carefully decipher this new component of the tumor microenvironment. Due to the low biomass, the study of tumor-associated microbiota poses technical, analytical, biological, and clinical challenges and must be approached as a whole. To date, several studies have begun to shed light on the composition, functions, and clinical relevance of the tumor-associated microbiota. This new piece of the tumor microenvironment puzzle could potentially change the way we think about and treat patients with cancer.

【 授权许可】

Unknown   
Copyright © 2023 Goubet