Left atrial appendage occlusion combined with cryoballoon or radiofrequency ablation: One-year follow-up comparison

Frontiers in Cardiovascular Medicine

Cardiovascular Medicine

Fu Yi¹  Qun Yan²  Miaoyang Hu²  Haitao Liu²  Lanyan Guo²  Yibo Ma² 

[1] Correspondence:;Department of Cardiology, Xijing Hospital, Air Force Medical University, Shaanxi, China;

关键词: atrial fibrillation;    left atrial appendage occlusion;    cryoballoon ablation;    radiofrequency ablation;    peri-device leak;   

DOI  :  10.3389/fcvm.2023.1153158

 received in 2023-01-29, accepted in 2023-04-10,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundA one-stop procedure involving catheter ablation and left atrial appendage occlusion (LAAO) is an option for high-risk atrial fibrillation patients. Few studies have reported the efficacy and safety of cryoballoon ablation (CBA) combined with LAAO, and no studies have compared the combination of LAAO with CBA or radiofrequency ablation (RFA).MethodsA total of 112 patients were enrolled in the present study; 45 patients received CBA combined with LAAO (group 1), and 67 patients received RFA combined with LAAO (group 2). Patient follow-up was performed for 1 year to detect peri-device leaks (PDLs) and safety outcomes (defined as a composite of peri-procedural and follow-up adverse events).ResultsThe number of PDLs at the median 59 days follow-up was comparable between the two groups (33.3% in group 1 vs. 37.3% in group 2, p = 0.693). Safety outcomes were also comparable between the two groups (6.7% in group 1 vs. 7.5% in group 2, p = 1.000). Multivariable regression showed that PDLs risk and safety outcomes were all similar between the two groups. Subgroup analysis of PDLs indicated no significant differences. Follow-up safety outcomes were related to anticoagulant medication, and patients without PDLs were more likely to discontinue antithrombotic therapy. The total procedure and ablation times were all significantly shorter for group 1.ConclusionWhen compared with left atrial appendage occlusion combined with radiofrequency, left atrial appendage occlusion combined with cryoballoon ablation has the same risk of peri-device leaks and safety outcomes, but the procedure time was significantly reduced.

【 授权许可】

Unknown   
© 2023 Ma, Guo, Hu, Yan, Liu and Yi.