Frontiers in Neurology | |
The role of the gut microbiota and fecal microbiota transplantation in neuroimmune diseases | |
Neurology | |
Yuan Wang1  He Ma1  Xueli Fan1  Qi Zheng1  Nan Wu1  Xue Zhang1  Xizhi Li1  Bin Liu2  | |
[1] Department of Neurology, Binzhou Medical University Hospital, Binzhou, China;Institute for Metabolic and Neuropsychiatric Disorders, Binzhou Medical University Hospital, Binzhou, China; | |
关键词: gut microbiota; fecal microbiota transplantation (FMT); neuroimmune diseases; myasthenia gravis (MG); multiple sclerosis (MS); neuromyelitis optica spectrum disorders (NMOSDs); autoimmune encephalitis (AIE); Guillain–Barré syndrome (GBS); | |
DOI : 10.3389/fneur.2023.1108738 | |
received in 2022-11-26, accepted in 2023-01-16, 发布年份 2023 | |
来源: Frontiers | |
【 摘 要 】
The gut microbiota plays a key role in the function of the host immune system and neuroimmune diseases. Alterations in the composition of the gut microbiota can lead to pathology and altered formation of microbiota-derived components and metabolites. A series of neuroimmune diseases, such as myasthenia gravis (MG), multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSDs), Guillain–Barré syndrome (GBS), and autoimmune encephalitis (AIE), are associated with changes in the gut microbiota. Microecological therapy by improving the gut microbiota is expected to be an effective measure for treating and preventing some neuroimmune diseases. This article reviews the research progress related to the roles of gut microbiota and fecal microbiota transplantation (FMT) in neuroimmune diseases.
【 授权许可】
Unknown
Copyright © 2023 Wu, Li, Ma, Zhang, Liu, Wang, Zheng and Fan.
【 预 览 】
Files | Size | Format | View |
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RO202310108012791ZK.pdf | 700KB | download |