Vision health perspectives on Breaking Bad: Ophthalmic sequelae of methamphetamine use disorder

Frontiers in Toxicology

Toxicology

Thomas A. Albini¹  Danny A. Mammo²  Steven Yeh³  Nam V. Nguyen³  Ronald R. Krueger³  Ye Huang³  Brent D. Timperley³  Brent R. Hayek⁴ 

[1] Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, United States;Cleveland Clinic, Cole Eye Institute, Cleveland, OH, United States;Department of Ophthalmology and Visual Sciences, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United States;North Georgia Eye Clinic, Gainesville, GA, United States;

关键词: methamphetamine;    vision loss;    ocular injury;    keratitis;    neurotoxicity;    retinopathy;   

DOI  :  10.3389/ftox.2023.1135792

 received in 2023-01-01, accepted in 2023-02-22,  发布年份 2023

来源: Frontiers

【 摘 要 】

Methamphetamine use has become a rampant public health issue that not only causes devastating consequences to the user but also poses a burden to surrounding communities. A spectrum of ophthalmic sequelae is associated with methamphetamine use and includes episcleritis, scleritis, corneal ulceration, panophthalmitis, endophthalmitis, retinal vasculitis, and retinopathy. In many instances, prompt recognition of the condition and associated infectious process and early initiation of antimicrobial therapy are crucial steps to preventing vision loss. In this review, we summarize the reported ocular complications that may result from methamphetamine use in addition to several postulated mechanisms regarding the ocular toxicity of methamphetamine. The increasing prevalence of methamphetamine use as a public health threat highlights the need for continued investigation of this ophthalmologic issue.

【 授权许可】

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Copyright © 2023 Huang, Nguyen, Mammo, Albini, Hayek, Timperley, Krueger and Yeh.