An Efficient Ultrasound-Assisted Synthesis of Cu/Zn Hybrid MOF Nanostructures With High Microbial Strain Performance

Frontiers in Bioengineering and Biotechnology

Bioengineering and Biotechnology

Indrajit Patra¹  Basim Al-Qargholi²  Taher Shahryari³  Narendra Pal Singh Chauhan⁴  Mohammadreza Moghaddam-manesh⁵  Gulnora Abdullaevna Abdieva⁶ 

[1] An Independent Researcher, NIT, Durgapur, India;Department of Biomedical Engineering, Al-Mustaqbal University College, Hilla, Iraq;Department of Environmental Health Engineering, Faculty of Health, Social Determinants of Health Research Centre, Birjand University of Medical Sciences, Birjand, Iran;Independent Researcher, Shrisela, India;Petrochemistry and Polymer Research Group, Chemistry and Petrochemistry Research Center, Standard Research Institute, Tehran, Iran;Teaching Assistant, Department of Internal Medicine, Samarkand State Medical Institute, Samarkand, Uzbekistan;

关键词: Cu/Zn MOF;    hybrid nanostructures;    ultrasound route;    antibacterial nanostructures;    antifungal activity;   

DOI  :  10.3389/fbioe.2022.861580

 received in 2022-01-26, accepted in 2022-04-25,  发布年份 2022

来源: Frontiers

【 摘 要 】

Metal organic frameworks (MOFs) are a promising choice for antibacterial and antifungal activity due to their composition, unique architecture, and larger surface area. Herein, the ultrasonic method was used to synthesize the Cu/Zn-MOF material as an effective hybrid nanostructure with ideal properties. SEM images were used to investigate the product’s morphology and particle size distribution. The XRD pattern revealed that the Cu/Zn hybrid MOF nanostructures had a smaller crystalline size distribution than pure Cu and Zn-MOF samples. Furthermore, the BET technique determined that the hybrid MOF nanostructures had a high specific surface area. TG analysis revealed that the hybrid MOF structures were more thermally stable than pure samples. The final product, with remarkable properties, was used as a new option in the field of antibacterial studies. Antibacterial activity was assessed using MIC and MBC against Gram negative and Gram positive strains, as well as antifungal activity using MIC and MFC. The antimicrobial properties of the synthesized Cu/Zn hybrid MOF nanostructures revealed that they were more effective than commercial drugs in some cases. This study’s protocol could be a new strategy for introducing new hybrid nanostructures with specific applications.

【 授权许可】

Unknown   
Copyright © 2022 Abdieva, Patra, Al-Qargholi, Shahryari, Chauhan and Moghaddam-manesh.