The Role of Multimodality Imaging in HIV-Associated Cardiomyopathy

Frontiers in Cardiovascular Medicine

Cardiovascular Medicine

Rimsha Rana¹  Monica Mukherjee²  Erin Goerlich²  Garima Sharma³  Allison G. Hays³  Ellise T. Gambahaya⁴  Blanche Cupido⁴  Sudipa Sarkar⁵  Shashwatee Bagchi⁶ 

[1] Department of Medicine, Georgetown University School of Medicine, Baltimore, MD, United States;Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States;Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States;Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD, United States;Division of Cardiology, Department of Medicine, University of Cape Town and Groote Schuur Hospital, Observatory, Cape Town, South Africa;Division of Endocrinology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States;Division of Infectious Disease and Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, United States;

关键词: human immunodeficiency virus;    cardiomyopathy;    echocardiography;    cardiac magnetic resonance imaging;    computed cardiac tomography;   

DOI  :  10.3389/fcvm.2021.811593

 received in 2021-11-09, accepted in 2021-12-30,  发布年份 2022

来源: Frontiers

【 摘 要 】

Despite marked advances in therapeutics, HIV infection remains a leading cause of morbidity and mortality worldwide. HIV infection is associated with cardiovascular complications including myocardial dysfunction. The description of HIV-associated cardiomyopathy (HIVAC) has evolved over time from a predominantly dilated cardiomyopathy with systolic dysfunction to one of subclinical diastolic dysfunction. Multimodality cardiovascular imaging plays an integral role in our understanding of the etiology and pathogenesis of HIVAC. Such imaging is also essential in the evaluation of individuals with chronic HIV disease who present with cardiac symptoms, especially of heart failure. In the present review, we will highlight current evidence for the role of multimodality imaging in establishing the diagnosis, etiology and pathophysiology of HIVAC as well as guiding treatment and assessing prognosis.

【 授权许可】

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Copyright © 2022 Gambahaya, Rana, Bagchi, Sharma, Sarkar, Goerlich, Cupido, Mukherjee and Hays.