Frontiers in Nutrition | |
Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods | |
Nutrition | |
Lillian Barros1  Luigi Lucini2  Gabriele Rocchetti3  Corneliu Tanase4  Gianina Crișan5  Mihai Babotă6  Alexandru Nicolescu7  Andrei Mocan7  Claudiu I. Bunea8  | |
[1] Centro de Investigação de Montanha, Instituto Politécnico de Bragança, Bragança, Portugal;Laboratório Associado Para a Sustentabilidade e Tecnologia em Regiões de Montanha (SusTEC), Instituto Politécnico de Bragança, Bragança, Portugal;Department for Sustainable Food Process, Università Cattolica del Sacro Cuore, Piacenza, Italy;Department of Animal Science, Food and Nutrition, Università Cattolica del Sacro Cuore, Piacenza, Italy;Department of Pharmaceutical Botany, Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Sciences and Technology of Târgu Mures, Târgu Mures, Romania;Department of Pharmaceutical Botany, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania;Department of Pharmaceutical Botany, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania;Department of Pharmaceutical Botany, Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Sciences and Technology of Târgu Mures, Târgu Mures, Romania;Department of Pharmaceutical Botany, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania;Laboratory of Chromatography, Institute of Advanced Horticulture Research of Transylvania, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania;Viticulture and Oenology Department, Advanced Horticultural Research Institute of Transylvania, Faculty of Horticulture and Business in Rural Development, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Cluj-Napoca, Romania; | |
关键词: bioaccessibility; nutraceuticals; functional foods; phytonutrients; polyphenols; carotenoids; | |
DOI : 10.3389/fnut.2023.1184535 | |
received in 2023-03-11, accepted in 2023-06-15, 发布年份 2023 | |
来源: Frontiers | |
【 摘 要 】
Nutraceuticals and functional foods are composed of especially complex matrices, with polyphenols, carotenoids, minerals, and vitamins, among others, being the main classes of phytochemicals involved in their bioactivities. Despite their wide use, further investigations are needed to certify the proper release of these phytochemicals into the gastrointestinal medium, where the bioaccessibility assay is one of the most frequently used method. The aim of this review was to gather and describe different methods that can be used to assess the bioaccessibility of nutraceuticals and functional foods, along with the most important factors that can impact this process. The link between simulated digestion testing of phytochemicals and their in vitro bioactivity is also discussed, with a special focus on the potential of developing nutraceuticals and functional foods from simple plant materials. The bioactive potential of certain classes of phytochemicals from nutraceuticals and functional foods is susceptible to different variations during the bioaccessibility assessment, with different factors contributing to this variability, namely the chemical composition and the nature of the matrix. Regardless of the high number of studies, the current methodology fails to assume correlations between bioaccessibility and bioactivity, and the findings of this review indicate a necessity for updated and standardized protocols.
【 授权许可】
Unknown
Copyright © 2023 Nicolescu, Babotă, Barros, Rocchetti, Lucini, Tanase, Mocan, Bunea and Crișan.
【 预 览 】
Files | Size | Format | View |
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RO202310107185022ZK.pdf | 1378KB | download |