Basal ganglia for beginners: the basic concepts you need to know and their role in movement control

Frontiers in Systems Neuroscience

Neuroscience

Rodrigo F. Oliveira¹  Gabriel S. Rocha¹  André M. Britto¹  Paulo L. A. G. Morais¹  Ivana A. T. Fonseca¹  Fausto P. Guzen¹  Dayane P. Araújo¹  Lucidio C. Oliveira¹  Marco A. M. Freire¹  Karina M. Paiva¹  José R. L. P. Cavalcanti² 

[1] Laboratory of Experimental Neurology, Department of Biomedical Sciences, State University of Rio Grande do Norte, Mossoró, Brazil;null;

关键词: basal ganglia;    substantia nigra;    striatum;    dopamine;    movement control;    movement disorders;   

DOI  :  10.3389/fnsys.2023.1242929

 received in 2023-06-20, accepted in 2023-07-21,  发布年份 2023

来源: Frontiers

【 摘 要 】

The basal ganglia are a subcortical collection of interacting clusters of cell bodies, and are involved in reward, emotional, and motor circuits. Within all the brain processing necessary to carry out voluntary movement, the basal nuclei are fundamental, as they modulate the activity of the motor regions of the cortex. Despite being much studied, the motor circuit of the basal ganglia is still difficult to understand for many people at all, especially undergraduate and graduate students. This review article seeks to bring the functioning of this circuit with a simple and objective approach, exploring the functional anatomy, neurochemistry, neuronal pathways, related diseases, and interactions with other brain regions to coordinate voluntary movement.

【 授权许可】

Unknown   
Copyright © 2023 Rocha, Freire, Britto, Paiva, Oliveira, Fonseca, Araújo, Oliveira, Guzen, Morais and Cavalcanti.