Lipid transfer protein syndrome in a Northern European patient: An unusual case report

Frontiers in Medicine

Medicine

J. Behrends¹  E. Albert²  T. Walsemann²  U. Jappe³ 

[1] Core Facility Fluorescence Cytometry, Research Center Borstel, Leibniz Lung Center, Borstel, Germany;Division of Clinical and Molecular Allergology, Research Center Borstel, Leibniz Lung Center, Airway Research Center North (ARCN), Member of the German Center for Lung Research, Borstel, Germany;Division of Clinical and Molecular Allergology, Research Center Borstel, Leibniz Lung Center, Airway Research Center North (ARCN), Member of the German Center for Lung Research, Borstel, Germany;Interdisciplinary Allergy Outpatient Clinic, Medical Clinic III - Pneumology, University of Lübeck, Lübeck, Germany;

关键词: non-specific lipid transfer protein;    LTP;    LTP syndrome;    food allergy;    basophil activation test;    exercise-induced anaphylaxis;   

DOI  :  10.3389/fmed.2023.1049477

 received in 2022-09-20, accepted in 2023-01-03,  发布年份 2023

来源: Frontiers

【 摘 要 】

Non-specific lipid transfer proteins (nsLTPs) as the primary sensitizer in plant-food allergic patients used to be seen primarily in the Mediterranean area. However, more recently, increasing numbers of clinically relevant sensitizations are being observed in Northern Europe. We herein report an unusual case of a woman who developed an anaphylactic reaction during a meal including a variety of different foods ranging from fruits and nuts to oats, wheat, and salmon. Allergy diagnostics showed no Bet v 1 sensitization but an nsLTP-mediated food allergy. Despite the much more prominent birch food syndrome in Central and Northern Europe, LTPs should be considered disease-causing agents, especially for patients developing severe reactions after consuming LTP-containing foods.

【 授权许可】

Unknown   
Copyright © 2023 Albert, Walsemann, Behrends and Jappe.