Digitizing tuberculosis treatment monitoring in Wuhan city, China, 2020–2021: Impact on medication adherence

Frontiers in Public Health

Public Health

Ye Xiao¹  Aashifa Yaqoob²  Hina Najmi³  Shuangyi Hou⁴  Mengxian Zhang⁴  Jianjun Ye⁴  Liping Zhou⁴  Tao Li⁵  Yinyin Xia⁵  Guiyang Wang⁶  Yuehua Li⁶ 

[1] Beijing SINOVO Power Technology LTD., Beijing, China;Common Management Unit (TB, HIV/AIDS & Malaria), Islamabad, Pakistan;University of Bergen, Bergen, Norway;Health Services Academy, Islamabad, Pakistan;Institute for Tuberculosis Control and Prevention, Hubei Provincial Center for Disease Control and Prevention, Wuhan, Hubei, China;National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China;Wuhan Pulmonary Hospital, Wuhan Institute for Tuberculosis Control, Wuhan, Hubei, China;

关键词: tuberculosis;    China;    medication adherence and treatment outcome;    digital adherence technology;    operational research;   

DOI  :  10.3389/fpubh.2023.1033532

 received in 2022-08-31, accepted in 2023-02-03,  发布年份 2023

来源: Frontiers

【 摘 要 】

IntroductionDigital technologies can improve adherence to tuberculosis (TB) treatment. We studied the impact of digitizing TB treatment monitoring on adherence among TB patients in Wuhan, China, during 2020-2021.MethodsWe compared an electronic system introduced to monitor TB medication adherence (e-Patient Service System; e-PSS) with the p paper-based standard of care (TB Control Information System; TCIS) in terms of prescribed TB treatment doses taken by patients and patient outcome after six months of follow up. We designed a cross sectional study using retrospective data for all drug susceptible pulmonary TB patients recorded on both systems. The main indicators were: compliant first follow up visit (within 3 days of start of treatment); medication adherence (80% or more of monthly doses taken); and end of treatment success ratio.ResultsA total of 1,576 TB patients were recorded in TCIS in July September, 2020 and 1,145 TB cases were included in e-PSS in January March, 2021. The distribution of patient demographic and clinical features was similar between the two groups. A larger proportion from the e-PSS group visited the community doctor in the first three days compared with the TCIS group (48.91 versus 29. 76 % respectively). Medication adherence was also higher in the e-PSS group during the 6 months of treatment than in the TCIS group (84. 28 versus 80.3 3 % respectively). Treatment success was 92.52% in the e-PSS group and 92.07% in the TCIS group. Multivariate logistic regress ion analysis demonstrated that adjusted odds ratios for compliant first follow up visit, medication adherence and favorable treatment outcome in the e-PSS versus TCIS groups were 2.94 (95% 2.47 3.50), 1.33 (95% 1.08 1.63), and 1. 12 (95% CL: 0.79 1.57) respectively.DiscussionThis study revealed improvements in TB care following an intervention to monitor treatment digitally in patients in Wuhan, China.

【 授权许可】

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Copyright © 2023 Zhang, Wang, Najmi, Yaqoob, Li, Xia, Ye, Hou, Xiao, Zhou and Li.