Short-term effects of air pollution and weather changes on the occurrence of acute aortic dissection in a cold region

Frontiers in Public Health

Public Health

Yanming Sun¹  Mingxin Wang¹  Bo Sun¹  Sizheng Peng¹  Tao Song¹  Jing Chen¹  Haiyu Zhang¹  Zhonghua Wang¹  Kai Du¹  Jing Liu²  Leilei Yin³  Hongyan Zhao⁴  Yuhui Sun⁵  Yingtao Zhang⁶  Jianrui Ding⁷  Zhaowen Qiu⁸ 

[1] Department of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China;Department of Cardiology, Harbin Second Hospital, Harbin, China;Department of Emergency, The First Affiliated Hospital of Harbin Medical University, Harbin, China;Department of Medical Record, The Second Affiliated Hospital of Harbin Medical University, Harbin, China;Department of Obstetrics and Gynecology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China;School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China;School of Computer Science and Technology, Harbin Institute of Technology, Weihai, Shandong, China;School of Information and Computer Engineering, Northeast Forestry University, Harbin, Heilongjiang, China;

关键词: weather;    environment;    temperature;    pollution;    acute aortic dissection;    COVID-19;   

DOI  :  10.3389/fpubh.2023.1172532

 received in 2023-02-23, accepted in 2023-07-13,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundAir pollution and severe weather conditions can adversely affect cardiovascular disease emergencies. Nevertheless, it remains unclear whether air pollutants and low ambient temperature can trigger the occurrence of acute aortic dissection (AAD) in cold regions.MethodsWe applied a retrospective analysis to assess the short-term effects of air pollution and ambient temperature on the occurrence of AAD in Harbin, China. A total of 564 AAD patients were enrolled from a major hospital in Harbin between January 1, 2017, and February 5, 2021. Weather condition data and air pollutant concentrations, including fine particulate matter smaller than 10 μm (PM10) and 2.5 μm in diameter (PM2.5), nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO), and ozone (O3), were collected every day. Conditional logistic regressions and correlation analysis were applied to analyze the relationship of environmental and atmospheric parameters with AAD occurrence at lags of 0 to 7 days. Specifically, we appraised the air quality index, CO, NO2, SO2, O3, PM10, PM2.5, temperature, dew point temperature, atmospheric pressure, and cloud amount.ResultsA total of 1,496 days at risk were assessed, of which 564 patients developed AAD. Specifically, AAD did not occur on 1,043 (69.72%) days, while 1 or more cases occurred on 453 (30.28%) days. Several pollution and weather predictors for AAD were confirmed by multilevel modeling. The air quality index (p = 0.0012), cloud amount (p = 0.0001), and concentrations of PM2.5 (p = 0.0004), PM10 (p = 0.0013), NO2 (p = 0.0007) and O3 (p = 0.0001) predicted AAD as early as 7 days before the incident (lag of 7 days) in the study period. However, only concentrations of the air pollutants NO2 (p = 0.0468) and O3 (p = 0.011) predicted the occurrence of AAD after the COVID-19 outbreak. Similar predictive effects were observed for temperature, dew point temperature, and atmospheric pressure (all p < 0.05) on all days.ConclusionThe risk of AAD is closely related to air pollution and weather characteristics in Harbin. While causation was not determined, the impact of air pollutants on the risk of AAD was reduced after the COVID-19 outbreak.

【 授权许可】

Unknown   
Copyright © 2023 Zhang, Yin, Zhang, Qiu, Peng, Wang, Sun, Ding, Liu, Du, Wang, Sun, Chen, Zhao, Song and Sun.