Managing ulcerative colitis after surgery

Frontiers in Medicine

Medicine

Iria Baston Rey¹  Cristina Calvino-Suarez¹  Rocío Ferreiro-Iglesias¹  Manuel Barreiro-de Acosta² 

[1] IBD Unit, Department of Gastroenterology, University Hospital Santiago de Compostela, Galicia, Spain;null;

关键词: pouchitis;    ulcerative colitis;    colectomy;    antibiotics;    biologic therapy;   

DOI  :  10.3389/fmed.2022.1081940

 received in 2022-10-27, accepted in 2022-12-05,  发布年份 2023

来源: Frontiers

【 摘 要 】

Management of ulcerative colitis after surgery suggested by guidelines (total proctocolectomy with ileal-pouch anal anastomosis) is a big challenge for physicians because patients who believed that their disease had been cured started experiencing very uncomfortable symptoms repeatedly. A high number of patients develop episodes of pouchitis, which is a non-specific inflammation of the pouch whose etiology is unknown. Antibiotics are the elective treatment for acute pouchitis, but regarding chronic pouchitis, this condition is very complicated to treat due to the absence of well-designed specific studies for this group of patients. Antibiotics, budesonide, and biological therapies are some of the recommended drugs for these patients, but despite their use, some need a permanent ileostomy.

【 授权许可】

Unknown   
Copyright © 2023 Calvino-Suarez, Ferreiro-Iglesias, Baston Rey and Barreiro-de Acosta.