The applications of functional materials-based nano-formulations in the prevention, diagnosis and treatment of chronic inflammation-related diseases

Frontiers in Pharmacology

Pharmacology

Yue Ming¹  Tingting Jiang¹  Dan Peng¹  Rui Ni¹  Yao Liu²  Jingjing Wang²  Hongjuan Cui³ 

[1] Department of pharmacy, Daping Hospital, Army Medical University, Chongqing, China;Department of pharmacy, Daping Hospital, Army Medical University, Chongqing, China;Medical Research Institute, Southwest University, Chongqing, China;Medical Research Institute, Southwest University, Chongqing, China;

关键词: nanotechnology;    chronic inflammation;    prevention;    diagnosis;    treatment;   

DOI  :  10.3389/fphar.2023.1222642

 received in 2023-05-15, accepted in 2023-07-17,  发布年份 2023

来源: Frontiers

【 摘 要 】

Chronic inflammation, in general, refers to systemic immune abnormalities most often caused by the environment or lifestyle, which is the basis for various skin diseases, autoimmune diseases, cardiovascular diseases, liver diseases, digestive diseases, cancer, and so on. Therapeutic strategies have focused on immunosuppression and anti-inflammation, but conventional approaches have been poor in enhancing the substantive therapeutic effect of drugs. Nanomaterials continue to attract attention for their high flexibility, durability and simplicity of preparation, as well as high profitability. Nanotechnology is used in various areas of clinical medicine, such as medical diagnosis, monitoring and treatment. However, some related problems cannot be ignored, including various cytotoxic and worsening inflammation caused by the nanomaterials themselves. This paper provides an overview of functional nanomaterial formulations for the prevention, diagnosis and treatment of chronic inflammation-related diseases, with the intention of providing some reference for the enhancement and optimization of existing therapeutic approaches.

【 授权许可】

Unknown   
Copyright © 2023 Wang, Ni, Jiang, Peng, Ming, Cui and Liu.