The efficacy of community-based exercise programs on circulating irisin level, muscle strength, cardiorespiratory endurance, and body composition for ischemic stroke: a randomized controlled trial

Frontiers in Neurology

Neurology

Dongheon Kang¹  Jiyoung Park²  Seon-Deok Eun² 

[1] Department of Healthcare and Public Health Research, National Rehabilitation Center, Ministry of Health and Welfare, Seoul, Republic of Korea;null;

关键词: stroke;    irisin;    muscle strength;    cardiorespiratory fitness;    disability;   

DOI  :  10.3389/fneur.2023.1187666

 received in 2023-03-17, accepted in 2023-06-16,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectiveWe investigated the changes in circulating irisin levels after community-based exercise and the association of these levels with improvements in muscle strength, cardiorespiratory endurance, and body composition in people with ischemic stroke.MethodsTwenty participants were randomly assigned to either a control or an exercise group. The community-based exercise program (CEP) consisted of 8 weeks of 1 h sessions for 3 days a week. Irisin levels, muscle strength, cardiorespiratory endurance, and body composition were assessed before and after the intervention.ResultsSignificant improvements were observed in the leg and trunk strength, peak oxygen consumption values, and body composition of the exercise group compared with the control group. In addition, circulating irisin levels were observed to have increased in the exercise group, positively correlated with muscle strength and cardiorespiratory endurance.ConclusionCEP might be an effective intervention to increase irisin levels and prevent a stroke-related decline in muscle function.

【 授权许可】

Unknown   
Copyright © 2023 Kang, Park and Eun.