Intravitreal methotrexate in type B lymphoblastic leukemia—Case Report

Frontiers in Oncology

Oncology

Mónica Ortiz Pérez¹  Maria Isabel Maya Naranjo¹  Sara Mesa Mesa¹  Sebastián Vallejo López²  Mariana López Posada²  María Elena González Alviar²  Martha Lía Gaviria Bravo² 

[1] Department of Ophthalmology, Universidad Pontificia Bolivariana, Medellín, Colombia;Department of Ophthalmology, Universidad de Antioquia, Medellín, Colombia;

关键词: methotrexate;    acute lymphoblastic leukemia;    intravitreal injection;    case report;    hypopion;   

DOI  :  10.3389/fonc.2023.1237204

 received in 2023-06-09, accepted in 2023-08-02,  发布年份 2023

来源: Frontiers

【 摘 要 】

Leukemia is a common neoplasia that, in its progress, can have ocular involvement due to direct infiltration or secondary to hematological alterations typical of the disease. These findings are consistent with an involvement of the central nervous system and are thus related to the prognosis. Despite the existing systemic therapies, there needs to be more literature that shows the treatment in the ocular involvement of this disease. A case report of a child with ocular involvement due to treatment-refractory acute lymphoblastic leukemia, successfully managed with intravitreal methotrexate, is presented.

【 授权许可】

Unknown   
Copyright © 2023 Maya Naranjo, Vallejo López, Mesa Mesa, Ortiz Pérez, López Posada, Gaviria Bravo and González Alviar