The instrumented single leg stance test detects early balance impairment in people with multiple sclerosis

Frontiers in Neurology

Neurology

Andreas Austeng¹  Frédéric Meyer¹  Pål Berg-Hansen²  Elisabeth Gulowsen Celius³  Stine Marit Moen⁴  Thomas Dahl Klyve⁴  Victor Gonzalez⁵  Trine Margrethe Seeberg⁵ 

[1] Department of Informatics, University of Oslo, Oslo, Norway;Department of Neurology, Oslo University Hospital, Oslo, Norway;Department of Neurology, Oslo University Hospital, Oslo, Norway;Institute of Clinical Medicine, University of Oslo, Oslo, Norway;MS Center Hakadal, Hakadal, Norway;SINTEF Digital, Smart Sensor and Micro Systems, Oslo, Norway;

关键词: multiple sclerosis;    single leg stance test;    inertial measurement units;    wearable sensors;    biomechanics;   

DOI  :  10.3389/fneur.2023.1227374

 received in 2023-05-23, accepted in 2023-06-28,  发布年份 2023

来源: Frontiers

【 摘 要 】

Balance impairment is frequent in people with multiple sclerosis (pwMS) and affects risk of falls and quality of life. By using inertial measurement units (IMUs) on the Single Leg Stance Test (SLS) we aimed to discriminate healthy controls (HC) from pwMS and detect differences in balance endurance and quality. Thirdly, we wanted to test the correlation between instrumented SLS parameters and self-reported measures of gait and balance. Fifty-five pwMS with mild (EDSS<4) and moderate disability (EDSS≥4) and 20 HC performed the SLS with 3 IMUs placed on the feet and sacrum and filled the Twelve Item Multiple Sclerosis Walking Scale (MSWS-12) questionnaire. A linear mixed model was used to compare differences in the automated balance measures. Balance duration was significantly longer in HC compared to pwMS (p < 0.001) and between the two disability groups (p < 0.001). Instrumented measures identified that trunk stability (normalized mediolateral and antero-posterior center of mass stability) had the strongest association with disability (R2 marginal 0.30, p < 0.001) and correlated well with MSWS-12 (R = 0.650, p < 0.001). PwMS tended to overestimate own balance compared to measured balance duration. The use of both self-reported and objective assessments from IMUs can secure the follow-up of balance in pwMS.

【 授权许可】

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Copyright © 2023 Berg-Hansen, Moen, Klyve, Gonzalez, Seeberg, Celius, Austeng and Meyer.