Frontiers in Public Health | |
Comparison of newly diagnosed COPD patients and the non-COPD residents in Shanghai Minhang District | |
Public Health | |
Qian Xu1  Shuang Yang2  Juan Xie3  Heyuan Ding4  Qingwu Jiang5  Shanshan Hou5  Xin Yin5  Na Wang5  Zhijun Jie6  Jindong Shi6  Junqing Li6  Zixuan Zheng6  Yue Dong7  Yi Zang8  | |
[1] Center for Disease Control and Prevention of Xuhui District, Shanghai, China;Center of Community-Based Health Research, Fudan University, Shanghai, China;Department of General Medicine, Jiangchuan Community Healthcare Service Center of Minhang District, Shanghai, China;Center of Community-Based Health Research, Fudan University, Shanghai, China;Department of General Medicine, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China;Department of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China;Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China;Department of Respiratory and Critical Care Medicine, Shanghai Fifth People‘s Hospital, Fudan University, Shanghai, China;Center of Community-Based Health Research, Fudan University, Shanghai, China;Department of Respiratory and Critical Care Medicine, Shanghai Fifth People‘s Hospital, Fudan University, Shanghai, China;Center of Community-Based Health Research, Fudan University, Shanghai, China;Lingang Laboratory, Shanghai, China;Lingang Laboratory, Shanghai, China; | |
关键词: chronic obstructive pulmonary disease; spirometry; screening; asymptomatic; general population; | |
DOI : 10.3389/fpubh.2023.1102509 | |
received in 2022-11-19, accepted in 2023-02-09, 发布年份 2023 | |
来源: Frontiers | |
【 摘 要 】
BackgroundTo compare whether the general population, especially those without characteristic symptoms, need spirometry screening for chronic obstructive pulmonary disease (COPD).MethodsResidents aged > 40 years old in Minhang, Shanghai, China, filled out screening questionnaires and underwent spirometry. The structured questionnaire integrating COPD population screening and COPD screening questionnaire was designed to obtain data on demographic characteristics, risk factors of COPD, respiratory symptoms, lifestyle habits, and comorbidities. We assessed the correlations between variables and COPD and the impact factors of FEV1% predicted.ResultsA total of 1,147 residents were included with a newly diagnosed mild to moderate COPD prevalence of 9.4% (108/1,147); half of the patients (54/108) were asymptomatic. Multivariate analysis did not reveal any significant differences in symptoms or lifestyle factors between newly diagnosed COPD patients and non-COPD participants. However, according to the generalized linear model, older age (β = −0.062, p < 0.001), male sex (β = −0.031, p = 0.047), and respiratory symptoms (β = −0.025, p = 0.013) were associated with more severe airflow limitation.ConclusionNewly diagnosed COPD patients had few differences compared with the general population, which suggests that a targeted case finding strategy other than general screening was currently preferred. More attention should be paid to respiratory symptoms when making a diagnosis and exploring new therapies and interventions for COPD in the early stage.
【 授权许可】
Unknown
Copyright © 2023 Yin, Zheng, Dong, Li, Yang, Xu, Hou, Zang, Ding, Xie, Jie, Jiang, Shi and Wang.
【 预 览 】
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