Dynamic changing smoking habits and cardiovascular events in patients newly diagnosed with hypertension, diabetes, or dyslipidemia: a national cohort study

Frontiers in Cardiovascular Medicine

Cardiovascular Medicine

Hye Ah Lee¹  Yeji Kim²  Junbeom Park²  Chang Mo Moon²  Bo Kyung Jeon²  Shinjeong Song² 

[1]Clinical Trial Center, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea

[2]Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea

关键词: smoking habits;    cardiovascular risk;    hypertension;    diabetes mellitus;    dyslipidemia;   

DOI  :  10.3389/fcvm.2023.1190227

 received in 2023-03-20, accepted in 2023-06-19,  发布年份 2023

来源: Frontiers

【 摘 要 】

Background and aimsThis study aimed to examine the association between dynamic smoking habit change and cardiovascular risk in a population newly diagnosed with hypertension, diabetes, and dyslipidemia.MethodsThis study included 49,320 individuals who had received health examinations provided by the Korea National Health Insurance Service. To determine the hazard ratios (HRs) and 95% confidence intervals (CIs) for incident major adverse cardiac events (MACE) and all-cause mortality based on dynamic smoking habit changes for 2 years, multivariable Cox proportional hazard models were utilized.ResultsDuring the follow-up, there were 1,004 (2.2%), 3,483 (7.6%), and 334 (0.7%) cases of myocardial infarction, stroke events, and cardiovascular death, respectively. The group with worsening smoking habits had an increased risk of cardiovascular events and death (HR: 1.33, 95% CI: 1.26–1.40) compared to improved smoking habits. The robustness of the results determined by a series of sensitivity analyses further strengthened the main findings.ConclusionsOur findings suggest that worsening of smoking habits, even for a short period of time, may increase the risk of myocardial infarction, stroke, and cardiovascular death in patients diagnosed with hypertension, diabetes, and dyslipidemia. For the primary prevention of cardiovascular events in patients with underlying diseases, dynamic modification of smoking habits should be actively considered.

【 授权许可】

Unknown   
© 2023 Song, Lee, Kim, Jeon, Moon and Park.