SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic

Frontiers in Veterinary Science

Veterinary Science

Louise Bach Kmetiuk¹  Alexander Welker Biondo¹  Annamaria Pratelli²  Nicola Decaro²  Violetta Vasinioti²  Fabrizia Valleriani³  Sara Capista³  Anna Serroni³  Barbara Bonfini³  Alessio Lorusso³  Kledir Anderson Hofstaetter Spohr⁴  Luciano Nakazato⁴  Samar Afif Jarrah⁴  Valéria Regia Franco Sousa⁴  Valéria Dutra⁴  Marco Tulio dos Santos⁴ 

[1] Department of Veterinary Medicine, Federal University of Paraná, Curitiba, PR, Brazil;Department of Veterinary Medicine, University of Bari, Valenzano, BA, Italy;Department of Virology, Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise “G. Caporale”, Teramo, TE, Italy;Laboratory of Molecular Biology, Federal University of Mato Grosso, Cuiabá, MT, Brazil;

关键词: Brazil;    companion animals;    pets;    serosurvey;    coronavirus;    SARS-CoV-2;   

DOI  :  10.3389/fvets.2023.1111728

 received in 2022-11-30, accepted in 2023-02-06,  发布年份 2023

来源: Frontiers

【 摘 要 】

SARS-CoV-2 was a worldwide threat during the COVID-19 pandemic, and the state of Mato Grosso had the second highest mortality rate in Brazil, with 427. 4 deaths/100,000 inhabitants. However, no large-scale study among dogs and cats in such highly infected areas of Brazil has so far been conducted. Accordingly, the present study reports on a serosurvey among dogs and cats in Cuiabá, capital of Mato Grosso from November 2020 to July 2021, where the human mortality rate was 605/100,000 at that time. Overall, 33/762 dogs (4.3%) and 4/182 cats (2.2%) were found to be seropositive for SARS-CoV-2 through ELISA, and 3/762 dogs (0.4%) and 3/182 cats (1.6%) were seropositive through the serum neutralization test. Cats presented higher seroprevalence with higher titers of neutralizing antibodies. Although N-protein based ELISA may be a good screening test, cross-reactivity with other canine coronaviruses may impair its diagnostic use among dogs.

【 授权许可】

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Copyright © 2023 Jarrah, Kmetiuk, Valleriani, Bonfini, Lorusso, Vasinioti, Decaro, dos Santos, Spohr, Pratelli, Serroni, Capista, Sousa, Biondo, Nakazato and Dutra.