Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart

Frontiers in Physiology

Physiology

Yunling Lin¹  Yifeng Huang¹  Jianshe Shi²  Huifang Liu²  Siyu Huang³  Wanni Xu⁴  Chao Liu⁴  Weifang Xie⁴  Yuguang Ye⁴  Daxin Zhu⁴  Jianlong Huang⁴  Lianta Su⁵ 

[1] Department of Diagnostic Radiology, Huaqiao University Affiliated Strait Hospital, Quanzhou, China;Department of General Surgery, Huaqiao University Affiliated Strait Hospital, Quanzhou, China;Department of Mathematics and Computer Science, Quanzhou Normal University, Quanzhou, China;Department of Mathematics and Computer Science, Quanzhou Normal University, Quanzhou, China;Fujian Provincial Key Laboratory of Data Intensive Computing, Quanzhou, China;Key Laboratory of Intelligent Computing and Information Processing, Fujian Province University, Quanzhou, China;Department of Mathematics and Computer Science, Quanzhou Normal University, Quanzhou, China;Key Laboratory of Intelligent Computing and Information Processing, Fujian Province University, Quanzhou, China;

关键词: cardiac MRI;    image segmentation;    U-Net;    batch normalization layer;    physiological analysis;   

DOI  :  10.3389/fphys.2023.1148717

 received in 2023-01-20, accepted in 2023-02-22,  发布年份 2023

来源: Frontiers

【 摘 要 】

Background and Objective: Cardiovascular disease is a high-fatality health issue. Accurate measurement of cardiovascular function depends on precise segmentation of physiological structure and accurate evaluation of functional parameters. Structural segmentation of heart images and calculation of the volume of different ventricular activity cycles form the basis for quantitative analysis of physiological function and can provide the necessary support for clinical physiological diagnosis, as well as the analysis of various cardiac diseases. Therefore, it is important to develop an efficient heart segmentation algorithm.Methods: A total of 275 nuclear magnetic resonance imaging (MRI) heart scans were collected, analyzed, and preprocessed from Huaqiao University Affiliated Strait Hospital, and the data were used in our improved deep learning model, which was designed based on the U-net network. The training set included 80% of the images, and the remaining 20% was the test set. Based on five time phases from end-diastole (ED) to end-systole (ES), the segmentation findings showed that it is possible to achieve improved segmentation accuracy and computational complexity by segmenting the left ventricle (LV), right ventricle (RV), and myocardium (myo).Results: We improved the Dice index of the LV to 0.965 and 0.921, and the Hausdorff index decreased to 5.4 and 6.9 in the ED and ES phases, respectively; RV Dice increased to 0.938 and 0.860, and the Hausdorff index decreased to 11.7 and 12.6 in the ED and ES, respectively; myo Dice increased to 0.889 and 0.901, and the Hausdorff index decreased to 8.3 and 9.2 in the ED and ES, respectively.Conclusion: The model obtained in the final experiment provided more accurate segmentation of the left and right ventricles, as well as the myocardium, from cardiac MRI. The data from this model facilitate the prediction of cardiovascular disease in real-time, thereby providing potential clinical utility.

【 授权许可】

Unknown   
Copyright © 2023 Xu, Shi, Lin, Liu, Xie, Liu, Huang, Zhu, Su, Huang, Ye and Huang.