Misdiagnosis of renal pelvic unicentric Castleman disease: a case report

Frontiers in Surgery

Surgery

Ming Yang¹  Liming Zhang²  Zhijia Liu³  Wen Cheng⁴  Zhenyu Xu⁴  Dian Fu⁵  Cheng Xue⁶  Zhiguo Mao⁶  Bo Yang⁷ 

[1] Department of Nephrology, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai, China;Department of Nephrology, Zhabei Central Hospital of JingAn District of Shanghai, Shanghai, China;Department of Urology, 8th medical Center of the PLA General Hospital, Beijing, China;Department of Urology, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, China;Department of Urology, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, China;Division of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai, China;Division of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai, China;Internal Medicine III (Nephrology), Naval Medical Center of PLA, Second Military Medical University (Naval Medical University), Shanghai, China;

关键词: Castleman disease;    renal tumor;    diagnosis;    computerized tomography;    imaging;   

DOI  :  10.3389/fsurg.2023.1225890

 received in 2023-05-20, accepted in 2023-08-18,  发布年份 2023

来源: Frontiers

【 摘 要 】

Castleman disease is a rare heterogeneous lymphoproliferative disorder of unknown etiology. Unicentric Castleman disease (UCD) is more common. UCD can occur at any site where lymphatic tissue exists, most commonly in the mediastinum, neck, and abdominal cavity, etc. in the current study, we reported a 46-year-old woman, who has left low back pain and discomfort. Magnetic resonance imaging (MRI) of the kidneys showed the left renal pelvis was occupied, left hydronephrosis, and the left renal hilum and retroperitoneal lymph nodes were enlarged. Enhanced kidney CT showed that the “pelvic tumor” was moderately enhanced in the bottom part in corticomedullary phase, while in nephrogenic phase, it was unevenly enhanced with a highly enhanced bottom part and weakly enhanced upper part. In excretory phase, reinforcement was decreased. “left renal pelvis tumor” was diagnosed and she underwent surgical treatment with left nephrectomy. However, histopathological examination indicated the UCD. We suggest that for renal pelvic tumors having imaging characteristics of homogeneous soft tissue density and heterogeneous CT enhancement, the hyaline vascular type of UCD could be taken into consideration for differential diagnosis.

【 授权许可】

Unknown   
© 2023 Fu, Yang, Yang, Xu, Cheng, Liu, Zhang, Mao and Xue.