Frailty among inpatients with Schizophrenia: Status, influencing factors, and their correlation with quality of life

Frontiers in Psychiatry

Psychiatry

Dongmei Wu¹  Xiaofeng Hou²  Cui Yang²  Xiucheng Ma² 

[1]Department of Nursing, The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China

[2]School of Nursing, Chengdu Medical College, Chengdu, China

关键词: frailty;    influencing factors;    quality of life;    correlation research;    Schizophrenia;   

DOI  :  10.3389/fpsyt.2022.1067260

 received in 2022-10-11, accepted in 2022-12-12,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectiveThis study aimed to understand frailty and its influencing factors in inpatients with Schizophrenia in Chengdu and to explore correlations between frailty and quality of life.MethodsFrom May to July 2022, inpatients with Schizophrenia were surveyed using a general information questionnaire, frailty phenotype (FP) scoring, the Self-Rating Depression Scale (SDS), the Mini-Mental State Examination (MMSE), and the SZ Quality of Life Scale (SQLS). Multivariate logistic regression was conducted to assess factors influencing frailty and multivariate linear regression was conducted to assess the factors influencing quality of life.ResultsA total of 556 hospitalized patients with Schizophrenia were included and divided into three groups according to the degree of frailty, of which 153 cases (27.5%) were without frailty, 348 cases (62.6%) were in early frailty, and 55 cases (9.9%) were in frailty. Univariate analysis of age, history of falls during hospitalization, polypharmacy, compulsory treatment during hospitalization, self-reported health status, activity level, cognitive impairment, depressive symptoms, “psychology and society,” “motivation and energy” and “symptoms and side-effects” showed statistically significant differences between the groups. Multinomial logistic regression showed that age, BMI, self-reported health, activity, cognitive impairment, motivation and energy, and symptoms and side-effects were influencing factors for frailty in hospitalized patients with Schizophrenia. Correlation analysis shows that frailty score positively correlated with SQLS score.ConclusionWe found that frailty was prevalent and that frailty was positively correlated with SQLS scores in inpatients with Schizophrenia. To effectively manage the frailty of hospitalized patients with Schizophrenia, medical staff should pay attention to its influencing factors and quality of life.

【 授权许可】

Unknown   
Copyright © 2023 Yang, Hou, Ma and Wu.