Birth size, growth trajectory and later cardio-metabolic risk

Frontiers in Endocrinology

Endocrinology

Chiara Cauzzo¹  Francesco Chiarelli¹  Valentina Chiavaroli²  Susanna Di Valerio² 

[1]Department of Pediatrics, University of Chieti, Chieti, Italy

[2]Neonatal Intensive Care Unit, Pescara Public Hospital, Pescara, Italy

关键词: intrauterine growth;    small for gestational age;    birth weight;    preterm;    cardiovascular risk;   

DOI  :  10.3389/fendo.2023.1187261

 received in 2023-03-15, accepted in 2023-05-19,  发布年份 2023

来源: Frontiers

【 摘 要 】

There is increasing evidence of a strong association between intrauterine growth and subsequent development of chronic disease in adult life. Birth size and growth trajectory have been demonstrated to have an impact on cardio-metabolic health, both in childhood and adult life. Hence, careful observation of the children’s growth pattern, starting from the intrauterine period and the first years of life, should be emphasized to detect the possible onset of cardio-metabolic sequelae. This allows to intervene on them as soon as they are detected, first of all through lifestyle interventions, whose efficacy seems to be higher when they are started early. Recent papers suggest that prematurity may constitute an independent risk factor for the development of cardiovascular disease and metabolic syndrome, regardless of birth weight. The purpose of the present review is to examine and summarize the available knowledge about the dynamic association between intrauterine and postnatal growth and cardio-metabolic risk, from childhood to adulthood.

【 授权许可】

Unknown   
Copyright © 2023 Cauzzo, Chiavaroli, Di Valerio and Chiarelli