期刊论文详细信息
Frontiers in Nutrition | |
Recent advances in analysis of capsaicin and its effects on metabolic pathways by mass spectrometry | |
Nutrition | |
Wuduo Zhao1  Zifang Peng1  Shusheng Zhang2  Wenfen Zhang3  Xu Zhang4  Jian Mao5  Jianping Xie5  Qidong Zhang5  | |
[1]College of Chemistry, Zhengzhou University, Zhengzhou, Henan, China | |
[2]College of Chemistry, Zhengzhou University, Zhengzhou, Henan, China | |
[3]Food Laboratory of Zhongyuan, Flavor Science Research Center of Zhengzhou University, Luohe, Henan, China | |
[4]College of Chemistry, Zhengzhou University, Zhengzhou, Henan, China | |
[5]Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, China | |
[6]School of Ecology and Environment, Zhengzhou University, Zhengzhou, Henan, China | |
[7]Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, Henan, China | |
[8]Food Laboratory of Zhongyuan, Flavor Science Research Center of Zhengzhou University, Luohe, Henan, China | |
关键词: capsaicin; mass spectrometry; food analysis; metabolic pathways; biological activities; | |
DOI : 10.3389/fnut.2023.1227517 | |
received in 2023-05-23, accepted in 2023-07-12, 发布年份 2023 | |
来源: Frontiers | |
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【 摘 要 】
Capsaicin is the main food active component in Capsicum that has gained considerable attention due to its broad biological activities, including antioxidation, anti-inflammation, anti-tumor, weight regulation, cardiac protection, anti-calculi, and diurnal-circadian regulation. The potent biological effects of capsaicin are intimately related to metabolic pathways such as lipid metabolism, energy metabolism, and antioxidant stress. Mass spectrometry (MS) has emerged as an effective tool for deciphering the mechanisms underlying capsaicin metabolism and its biological impacts. However, it remains challenging to accurately identify and quantify capsaicin and its self-metabolites in complex food and biological samples, and to integrate multi-omics data generated from MS. In this work, we summarized recent advances in the detection of capsaicin and its self-metabolites using MS and discussed the relevant MS-based studies of metabolic pathways. Furthermore, we discussed current issues and future directions in this field. In-depth studies of capsaicin metabolism and its physiological functions based on MS is anticipated to yield new insights and methods for preventing and treating a wide range of diseases.【 授权许可】
Unknown
Copyright © 2023 Peng, Zhang, Zhang, Mao, Zhang, Zhao, Zhang and Xie.
【 预 览 】
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RO202310104083625ZK.pdf | 385KB | ![]() |