Recent advances in nanoparticle applications in respiratory disorders: a review

Frontiers in Pharmacology

Pharmacology

Mohsen Qayoomian¹  Mohammad Ehsan Taghavizadeh Yazdi¹  Mohammad Hossein Boskabady²  Sima Beigoli³ 

[1] Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Mashhad University of Medical Sciences, Mashhad, Razavi Khorasan, Iran;

关键词: nanomedicine;    nanoparticle;    respiratory disorders;    drug delivery;    treatment;   

DOI  :  10.3389/fphar.2023.1059343

 received in 2022-10-01, accepted in 2023-05-30,  发布年份 2023

来源: Frontiers

【 摘 要 】

Various nanoparticles are used in the discovery of new nanomedicine to overcome the shortages of conventional drugs. Therefore, this article presents a comprehensive and up-to-date review of the effects of nanoparticle-based drugs in the treatment of respiratory disorders, including both basic and clinical studies. Databases, including PubMed, Web of Knowledge, and Scopus, were searched until the end of August 2022 regarding the effect of nanoparticles on respiratory diseases. As a new tool, nanomedicine offered promising applications for the treatment of pulmonary diseases. The basic composition and intrinsic characteristics of nanomaterials showed their effectiveness in treating pulmonary diseases. The efficiency of different nanomedicines has been demonstrated in experimental animal models of asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis (PF), lung cancer, lung infection, and other lung disorders, confirming their function in the improvement of respiratory disorders. Various types of nanomaterials, such as carbon nanotubes, dendrimers, polymeric nanomaterials, liposomes, quantum dots, and metal and metal oxide nanoparticles, have demonstrated therapeutic effects on respiratory disorders, which may lead to new possible remedies for various respiratory illnesses that could increase drug efficacy and decrease side effects.

【 授权许可】

Unknown   
Copyright © 2023 Taghavizadeh Yazdi, Qayoomian, Beigoli and Boskabady.