Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions

Frontiers in Nutrition

Nutrition

Binsheng He¹  Bo Wang²  Jia Xiang²  Songwen Tan²  Wenhu Zhou² 

[1] Academician Workstation, Changsha Medical University, Changsha, China;Academician Workstation, Changsha Medical University, Changsha, China;Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, China;

关键词: natural ingredients;    spray drying;    dry powder inhalation;    factors influencing DPI;    application of natural extracts;   

DOI  :  10.3389/fnut.2023.1190912

 received in 2023-03-21, accepted in 2023-06-19,  发布年份 2023

来源: Frontiers

【 摘 要 】

Natural ingredients have many applications in modern medicine and pharmaceutical projects. However, they often have low solubility, poor chemical stability, and low bioavailability in vivo. Spray drying technology can overcome these challenges by enhancing the properties of natural ingredients. Moreover, drug delivery systems can be flexibly designed to optimize the performance of natural ingredients. Among the various drug delivery systems, dry powder inhalation (DPI) has attracted much attention in pharmaceutical research. Therefore, this review will focus on the spray drying of natural ingredients for DPI and discuss their synthesis and application.

【 授权许可】

Unknown   
Copyright © 2023 Wang, Xiang, He, Tan and Zhou.