Occupation-modulated language networks and its lateralization: A resting-state fMRI study of seafarers

Frontiers in Human Neuroscience

Neuroscience

Yang Yang¹  Min Xu²  Hongjie Yan³  Weiming Zeng⁴  Huijun Wu⁵  Deyuan Peng⁵  Chunqi Chang⁶  Nizhuan Wang⁷ 

[1] CAS Key Laboratory of Behavioral Science, Center for Brain Science and Learning Difficulties, Institute of Psychology, Chinese Academy of Sciences, Beijing, China;Center for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen, China;Department of Neurology, Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, China;Lab of Digital Image and Intelligent Computation, Shanghai Maritime University, Shanghai, China;School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China;School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China;Peng Cheng Laboratory, Shenzhen, China;School of Biomedical Engineering, ShanghaiTech University, Shanghai, China;

关键词: functional magnetic resonance imaging;    lateralization;    occupational neuroplasticity;    occupation;    language network;    seafarers;   

DOI  :  10.3389/fnhum.2023.1095413

 received in 2022-11-11, accepted in 2023-02-27,  发布年份 2023

来源: Frontiers

【 摘 要 】

IntroductionStudies have revealed that the language network of Broca’s area and Wernicke’s area is modulated by factors such as disease, gender, aging, and handedness. However, how occupational factors modulate the language network remains unclear.MethodsIn this study, taking professional seafarers as an example, we explored the resting-state functional connectivity (RSFC) of the language network with seeds (the original and flipped Broca’s area and Wernicke’s area).ResultsThe results showed seafarers had weakened RSFC of Broca’s area with the left superior/middle frontal gyrus and left precentral gyrus, and enhanced RSFC of Wernicke’s area with the cingulate and precuneus. Further, seafarers had a less right-lateralized RSFC with Broca’s area in the left inferior frontal gyrus, while the controls showed a left-lateralized RSFC pattern in Broca’s area and a right-lateralized one in Wernicke’s area. Moreover, seafarers displayed stronger RSFC with the left seeds of Broca’s area and Wernicke’s area.DiscussionThese findings suggest that years of working experience significantly modulates the RSFC of language networks and their lateralization, providing rich insights into language networks and occupational neuroplasticity.

【 授权许可】

Unknown   
Copyright © 2023 Wu, Peng, Yan, Yang, Xu, Zeng, Chang and Wang.