Contribution of microvascular dysfunction to chronic pain

Frontiers in Pain Research

Pain Research

Terence J. Coderre¹ 

[1] Correspondence:;

关键词: endothelial cells;    microvascular injury;    ischemia-reperfusion;    oxidative stress;    antioxidants;    cytokines;   

DOI  :  10.3389/fpain.2023.1111559

 received in 2022-11-29, accepted in 2023-01-09,  发布年份 2023

来源: Frontiers

【 摘 要 】

There is growing evidence that microvascular dysfunction is a pathology accompanying various injuries and conditions that produce chronic pain and may represent a significant contributing factor. Dysfunction that occurs within each component of the microvasculature, including arterioles, capillaries and venules impacts the health of surrounding tissue and produces pathology that can both initiate pain and influence pain sensitivity. This mini review will discuss evidence for a critical role of microvascular dysfunction or injury in pathologies that contribute to chronic pain conditions such as complex regional pain syndrome (CRPS) and fibromyalgia.

【 授权许可】

Unknown   
© 2023 Coderre.