Lasting impairments following transient ischemic attack and minor stroke: a systematic review protocol

Frontiers in Neurology

Neurology

Neil Heron¹  Jennifer Crow²  Boris Modrau³  Birgitte Hede Ebbesen⁴  Grace Turner⁵  Conni Skrubbeltrang⁶  Eirini Kontou⁷  Emma Finch⁸  Tenelle Hodson⁹  Gary Crowfoot^1,10 

[1] Centre for Public Health, Queen’s University Belfast, Belfast, Ireland;School of Medicine, Keele University, Staffordshire, United Kingdom;Department of Brain Sciences, Imperial College London, Imperial College Healthcare NHS Trust, London, United Kingdom;Department of Neurology, Aalborg University Hospital, Aalborg University, Aalborg, Denmark;Department of Physiotherapy and Occupational Therapy, Aalborg University Hospital, Aalborg, Denmark;Department of Health Science and Technology, Aalborg University, Aalborg, Denmark;Department of Neurology, Aalborg University Hospital, Aalborg University, Aalborg, Denmark;Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom;Medical Library, Aalborg University Hospital, Aalborg, Denmark;Mental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United Kingdom;Institute of Mental Health, Nottinghamshire Healthcare NHS Foundation Trust, Nottingham, United Kingdom;Research and Innovation, West Moreton Health, Ipswich, QLD, Australia;Speech Pathology Department, Princess Alexandra Hospital, Woolloongabba, QLD, Australia;School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, QLD, Australia;School of Health Sciences and Social Work and The Hopkins Centre, Menzies Health Institute Queensland, Griffith University, Nathan, QLD, Australia;School of Nursing and Midwifery, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW, Australia;

关键词: transient ischemic attack;    TIA;    minor stroke;    mild stroke;    impairments;    systematic review;    protocol;   

DOI  :  10.3389/fneur.2023.1177309

 received in 2023-03-01, accepted in 2023-04-20,  发布年份 2023

来源: Frontiers

【 摘 要 】

IntroductionThe focus on medical management and secondary prevention following Transient Ischemic Attack (TIA) and minor stroke is well-established. Evidence is emerging that people with TIA and minor stroke can experience lasting impairments as fatigue, depression, anxiety, cognitive impairment, and communication difficulties. These impairments are often underrecognized and inconsistently treated. Research in this area is developing rapidly and an updated systematic review is required to evaluate new evidence as it emerges. This living systematic review aims to describe the prevalence of lasting impairments and how they affect the lives of people with TIA and minor stroke. Furthermore, we will explore whether there are differences in impairments experienced by people with TIA compared to minor stroke.MethodsSystematic searches of PubMed, EMBASE, CINAHL, PsycINFO, Cochrane Libraries will be undertaken. The protocol will follow the Cochrane living systematic review guideline with an update annually. A team of interdisciplinary reviewers will independently screen search results, identify relevant studies based on the defined criteria, conduct quality assessments, and extract data. This systematic review will include quantitative studies on people with TIA and/or minor stroke that report on outcomes in relation to fatigue, cognitive and communication impairments, depression, anxiety, quality of life, return to work/education, or social participation. Where possible, findings will be grouped for TIA and minor stroke and collated according to the time that follow-up occurred (short-term < 3 months, medium-term 3–12 months, and long-term > 12 months). Sub-group analysis on TIA and minor stroke will be performed based on results from the included studies. Data from individual studies will be pooled to perform meta-analysis where possible. Reporting will follow the Preferred Reporting Items for Systematic review and Meta-Analysis Protocol (PRISMA-P) guideline.PerspectivesThis living systematic review will collate the latest knowledge on lasting impairments and how these affect the lives of people with TIA and minor stroke. It will seek to guide and support future research on impairments emphasizing distinctions between TIA and minor stroke. Finally, this evidence will allow healthcare professionals to improve follow-up care for people with TIA and minor stroke by supporting them to identify and address lasting impairments.

【 授权许可】

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Copyright © 2023 Hede Ebbesen, Modrau, Kontou, Finch, Crowfoot, Crow, Heron, Hodson, Skrubbeltrang and Turner.