Progress in drug delivery and diagnostic applications of carbon dots: a systematic review

Frontiers in Chemistry

Chemistry

Sandeep Sheth¹  Amit Bansal²  Hemlata Kaurav³  Deepak N. Kapoor³  Dhriti Verma³ 

[1] Department of Pharmaceutical Sciences, College of Pharmacy, Larkin University, Miami, FL, United States;Formulation Research and Development, Perrigo Company Plc, Allegan, MI, United States;School of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India;

关键词: carbon dots;    drug delivery;    gene delivery;    nanocarriers;    bioimaging;   

DOI  :  10.3389/fchem.2023.1227843

 received in 2023-05-23, accepted in 2023-07-05,  发布年份 2023

来源: Frontiers

【 摘 要 】

Carbon dots (CDs), which have particle size of less than 10 nm, are carbon-based nanomaterials that are used in a wide range of applications in the area of novel drug delivery in cancer, ocular diseases, infectious diseases, and brain disorders. CDs are biocompatible, eco-friendly, easy to synthesize, and less toxic with excellent chemical inertness, which makes them very good nanocarrier system to deliver multi-functional drugs effectively. A huge number of researchers worldwide are working on CDs-based drug delivery systems to evaluate their versatility and efficacy in the field of pharmaceuticals. As a result, there is a tremendous increase in our understanding of the physicochemical properties, diagnostic and drug delivery aspects of CDs, which consequently has led us to design and develop CDs-based theranostic system for the treatment of multiple disorders. In this review, we aim to summarize the advances in application of CDs as nanocarrier including gene delivery, vaccine delivery and antiviral delivery, that has been carried out in the last 5 years.

【 授权许可】

Unknown   
Copyright © 2023 Kaurav, Verma, Bansal, Kapoor and Sheth.