Quality-of-life impact of interstitial cystitis and other pelvic pain syndromes

Frontiers in Pain Research

Pain Research

Andrew R. Cunningham¹  Jayoung Kim²  Alexandra Dubinskaya²  Jennifer T. Anger³  Kamil E. Barbour⁴  Lin Gu⁵  Amanda M. De Hoedt⁵  Stephen J. Freedland⁶ 

[1] Brody School of Medicine, East Carolina University, Greenville, NC, United States;Durham VA Health Care System, Veterans Health Administration, United States Department of Veterans Affairs, Durham, NC, United States;Department of Urology, Cedars Sinai Medical Center, Los Angeles, CA, United States;Department of Urology, University of California, San Diego, La Jolla, CA, United States;Division of Population Health, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States;Durham VA Health Care System, Veterans Health Administration, United States Department of Veterans Affairs, Durham, NC, United States;Durham VA Health Care System, Veterans Health Administration, United States Department of Veterans Affairs, Durham, NC, United States;Department of Urology, Cedars Sinai Medical Center, Los Angeles, CA, United States;Center for Integrated Research on Cancer and Lifestyle, Cedars Sinai Medical Center, Los Angeles, CA, United States;

关键词: intersticial cystitis;    bladder pain syndrome;    IC/BPS;    pelvic pain;    veterans;   

DOI  :  10.3389/fpain.2023.1149783

 received in 2023-01-23, accepted in 2023-05-11,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectiveTo compare health-related quality of life (HRQOL) and pelvic pain levels over time in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) and those with other pelvic pain conditions (OPPC) including chronic prostatitis, dyspareunia, vaginismus, vulvodynia, and vulvar vestibulitis.MethodsWe prospectively enrolled male and female patients from any Veterans Health Administration (VHA) center in the US. They completed the Genitourinary Pain Index (GUPI) quantifying urologic HRQOL and the 12-Item Short Form Survey version 2 (SF-12) quantifying general HRQOL at enrollment and 1 year later. Participants were classified by ICD diagnosis codes and confirmed by chart review to be IC/BPS or OPPC (308 and 85 patients respectively).ResultsAt baseline and follow-up, IC/BPS patients, on average, had worse urologic and general HRQOL than OPPC patients. IC/BPS patients demonstrated improvement in urologic HRQOL measures over the study but demonstrated no significant change in any general HRQOL measure suggesting a condition-specific impact. Patients with OPPC demonstrated similar improvements in urologic HRQOL but had deteriorating mental health and general HRQOL at follow-up suggesting a wider general HRQOL impact for these diseases.ConclusionsWe found that patients with IC/BPS had worse urologic HRQOL compared to other pelvic conditions. Despite this, IC/BPS showed stable general HRQOL over time, suggesting a more condition-specific impact on HRQOL. OPPC patients showed deteriorating general HRQOL, suggesting more widespread pain symptoms in these conditions.

【 授权许可】

Unknown   
© 2023 Cunningham, Gu, Dubinskaya, De Hoedt, Barbour, Kim, Freedland and Anger.