Evaluation and management of symptomatic duodenal diverticula: a single-center retrospective analysis of 647 patients

Frontiers in Surgery

Surgery

Zheng Wang¹  Fan Chen¹  Jie Li¹  Jiaqiang Ren¹  Liang Han¹  Zheng Wu¹  Shuai Wu¹  Jiachun Ding¹  Tong Su² 

[1] Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China;School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China;

关键词: duodenal diverticula;    symptomatic patients;    diverticular size;    biliary comorbidities;    surgical treatment;   

DOI  :  10.3389/fsurg.2023.1267436

 received in 2023-07-26, accepted in 2023-08-21,  发布年份 2023

来源: Frontiers

【 摘 要 】

AimsTo explore the clinical characteristics of patients with symptomatic duodenal diverticula and to generalize how to make appropriate treatment choices for this group of patients.Materials and methodsFrom January 2010 to September 2020, a total of 647 patients with duodenal diverticula (DD) were included in this study. 345 of them with relevant symptoms were divided into the symptomatic group and the other 302 patients were in the asymptomatic group.ResultsAmong all patients, most DD were located in the periampullary area, <1 cm in size, and single in number. The distribution of DD localized in the 2nd portion/periampullary (P = 0.002/P < 0.001) and with a 1 cm size cut-off value (P = 0.003) was significantly different between the symptomatic and asymptomatic groups. Multivariate Logistics analysis further suggests that diverticular size (<1 cm, 1–3 cm) and combined biliary comorbidities (bile duct stones and gallstones, primary bile duct stones, cholangitis without bile duct stones) may be factors influencing the choice of treatment modality. Of all patients undergoing surgical treatment, a total of 7 cases developed various postoperative complications, and no one died.ConclusionsPatients with DD ≥1 cm or located in the periampullary were more likely to be symptomatic. The specific size of the DD and the combination of specific biliary comorbidities may have an impact on the choice of treatment modality.

【 授权许可】

Unknown   
© 2023 Ren, Ding, Su, Wu, Chen, Li, Wang, Han and Wu.