Association between air pollutants and birth defects in Xiamen, China

Frontiers in Pediatrics

Pediatrics

Jiawen Qi¹  Xiaohui Ma¹  Qiliang Cheng¹  Zhimeng Huang¹  Jinzhun Wu¹  Yue Qiu² 

[1] Department of Pediatrics, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, China;Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Xiamen, China;

关键词: birth defects;    air pollution;    etiology;    China;    congenital heart disease;   

DOI  :  10.3389/fped.2023.1132885

 received in 2022-12-28, accepted in 2023-05-11,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectiveTo explore the relationship between common air pollution and common birth defects, and to provide reference for the prevention of birth defects.MethodsWe conducted a case-control study in Xiamen, a city in southeastern China from 2019 to 2020. Logistics regression was used to analyze the relationship between sulfur dioxide(SO2), fine particulate matter 2.5(PM2.5), nitrogen dioxide(NO2), ozone(O3), carbon monoxide(CO) and the occurrence of common birth defects such as congenital heart disease, facial cleft, and finger deformity.ResultsSO2 significantly increased the risk of birth defects such as congenital heart disease, cleft lip and/or cleft palate, and ear deformity in the first and second months of pregnancy.ConclusionExposure to common air pollutants increases the risk of birth defects, and SO2 significantly affects the occurrence of birth defects in the first two months of pregnancy.

【 授权许可】

Unknown   
© 2023 Huang, Qiu, Qi, Ma, Cheng and Wu.