Sources, morphology, phytochemistry, pharmacology of Curcumae Longae Rhizoma, Curcumae Radix, and Curcumae Rhizoma: a review of the literature

Frontiers in Pharmacology

Pharmacology

Lu-yao Zheng¹  Min Li¹  Ting Wang²  Li Li²  Zhu-jun Yin²  Yun-yun Quan²  Shi-qi Feng²  Xin Zhu³  Jun-ning Zhao³ 

[1] Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu, China;Sichuan Academy of Chinese Medicine Sciences, Sichuan Institute for Translational Chinese Medicine, Biological Assay Key Laboratory of State Administration of Traditional Chinese Medicine for Traditional Chinese Medicine Quality, Translational Chinese Medicine Key Laboratory of Sichuan Province, Sichuan Engineering Technology Research Center of Genuine Regional Drug, Engineering Research Center for Formation Principle and Quality Evaluation of Genuine Medicinal Materials in Sichuan Province, Chengdu, China;Sichuan Academy of Chinese Medicine Sciences, Sichuan Institute for Translational Chinese Medicine, Biological Assay Key Laboratory of State Administration of Traditional Chinese Medicine for Traditional Chinese Medicine Quality, Translational Chinese Medicine Key Laboratory of Sichuan Province, Sichuan Engineering Technology Research Center of Genuine Regional Drug, Engineering Research Center for Formation Principle and Quality Evaluation of Genuine Medicinal Materials in Sichuan Province, Chengdu, China;Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu, China;

关键词: Curcumae Longae Rhizoma;    Curcumae Radix;    Curcumae Rhizoma;    pharmacology;    curcumin;    targets;   

DOI  :  10.3389/fphar.2023.1229963

 received in 2023-05-27, accepted in 2023-08-15,  发布年份 2023

来源: Frontiers

【 摘 要 】

Curcumae Longae Rhizoma (turmeric), Curcumae Radix and Curcumae Rhizoma are derived from the Curcuma species, and have gradually become three of the most commonly used medicinal herbs in China due to their different origins, processing methods and medicinal part. These three herbs have certain similarities in morphology, chemical composition, and pharmacological effects. All three of these herbs contain curcuminoids and volatile oil compounds, which exhibit anti-inflammatory, anti-tumor, antioxidant, and neuroprotective properties, although modern clinical applications have their own requirements. At present, there is no systematic guidelines for the clinical application of these three of Curcuma species; consequently, there is a high risk of unwanted phenomena associated with the mixing and indiscriminate use of these herbs. In this review, we focus predominantly on morphology, chemical composition, and the pharmacological activity of these three Curcuma herbs and summarize the current status of research in this field. Our goal is to provide a better understanding of clinical value of these Curcuma species so that we can provide reference guidelines for their further development, utilization and rational clinical application.

【 授权许可】

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Copyright © 2023 Zhu, Quan, Yin, Li, Wang, Zheng, Feng, Zhao and Li.