Potential of macronutrients and probiotics to boost immunity in patients with SARS-COV-2: a narrative review

Frontiers in Nutrition

Nutrition

Saeid Doaei¹  Maryam Zare²  Afrouz Mardi³  Farhad Pourfarzi⁴  Negin Abediasl⁴  Daniel Hackett⁵  Azadeh Hajipour⁶  Aziz Kamran⁷ 

[1] Department of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran;Department of Nutrition, Khalkhal University of Medical Sciences, Khalkhal, Iran;Department of Public Health, School of Health, Ardabil University of Medical Science, Ardabil, Iran;Digestive Disease Research Center, Ardabil University of Medical Sciences, Ardabil, Iran;Physical Activity, Lifestyle, Ageing and Wellbeing Faculty Research Group, School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Lidcombe, NSW, Australia;School of Health, Qazvin University of Medical Sciences, Qazvin, Iran;School of Medicine and Allied Medical Sciences, Ardabil University of Medical Sciences, Ardabil, Iran;

关键词: protein;    lipid;    carbohydrate;    probiotic;    immune system;    SARS-CoV-2;   

DOI  :  10.3389/fnut.2023.1161894

 received in 2023-02-08, accepted in 2023-04-26,  发布年份 2023

来源: Frontiers

【 摘 要 】

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) may cause inflammation and increased cytokine secretion. Dietary factors may play an important role in enhancing the immune responses against infectious diseases such as SARS-COV-2. This narrative review aims to determine the effectiveness of macronutrients and probiotics to improve immunity in SARS-COV-2 patients. Dietary proteins may boost pulmonary function in SARS-COV-2 patients through inhibitory effects on the Angiotensin-converting enzyme (ACE) and reduce Angiotensin (ANG-II). Moreover, omega-3 fatty acids may improve oxygenation, acidosis, and renal function. Dietary fiber may also produce anti-inflammatory effects by reducing the level of high-sensitivity C-Reactive Protein (hs-CRP), Interleukin (IL-6), and Tumor necrosis factor (TNF-α). In addition, some evidence indicates that probiotics significantly improve oxygen saturation which may enhance survival rate. In conclusion, the consumption of a healthy diet including adequate macronutrients and probiotic intake may decrease inflammation and oxidative stress. Following this dietary practice is likely to strengthen the immune system and have beneficial effects against SARS-COV-2.

【 授权许可】

Unknown   
Copyright © 2023 Mardi, Kamran, Pourfarzi, Zare, Hajipour, Doaei, Abediasl and Hackett.