The in vivo and in vitro corrosion behavior of MgO/Mg-Zn-Ca composite with different Zn/Ca ratio

Frontiers in Bioengineering and Biotechnology

Bioengineering and Biotechnology

Qi Wang¹  Weihao Zhang¹  Fengxin Zhou¹  Chenguang Li¹  Feng Xue¹  Chaokun Tang²  Shaoyuan Lyu²  Minfang Chen³  Jiangtao Feng⁴  Hao Wang⁴  Baoshan Xu⁴  Shuquan Zhang⁴ 

[1] Department of Orthopedics, Integrated Chinese and Western Medicine Hospital, Tianjin University, Tianjin, China;School of Materials Science and Engineering, Tianjin University of Technology, Tianjin, China;School of Materials Science and Engineering, Tianjin University of Technology, Tianjin, China;National Demonstration Center for Experimental Function Materials Education, Tianjin, China;Key Laboratory of Display Materials and Photoelectric Device (Ministry of Education), Tianjin, China;Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China;

关键词: MgO/Mg-Zn-Ca composite;    in vivo;    in vitro;    second phase corrosion;    bone growth;   

DOI  :  10.3389/fbioe.2023.1222722

 received in 2023-05-15, accepted in 2023-06-16,  发布年份 2023

来源: Frontiers

【 摘 要 】

The effect of Zn/Ca ratio on the corrosion behavior of Mg–3Zn-0.2Ca-1.0MgO (3ZX) and Mg–1Zn-0.2Ca-1.0MgO (ZX) was investigated on the as-extruded specimens. Microstructure observations revealed that the low Zn/Ca ratio led to the grain growth from 1.6 µm in 3ZX to 8.1 µm in ZX. At the same time, the low Zn/Ca ratio changed the nature of second phase from the existence of Mg-Zn and Ca2Mg6Zn3 phases in 3ZX to the dominated Ca2Mg6Zn3 phase in ZX. The local galvanic corrosion caused by the excessive potential difference was alleviated obviously due to the missing of MgZn phase in ZX. Besides, the in vivo experiment also showed that ZX composite exhibited a good corrosion performance and the bone tissue around the implant grew well.

【 授权许可】

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Copyright © 2023 Zhang, Tang, Feng, Wang, Li, Zhang, Zhou, Xue, Xu, Lyu, Chen and Wang.