Downgrade BI-RADS 4A Patients Using Nomogram Based on Breast Magnetic Resonance Imaging, Ultrasound, and Mammography

Frontiers in Oncology

Oncology

Shaoyun Zong¹  Weimin Chai²  Ying Zhu³  Xiaoxiao Zhang³  Weiwei Zhan³  Shangyan Xu³  Yamie Xie⁴ 

[1] College of Medicine, Kunming University of Science and Technology, Department of Ultrasound, The First People’s Hospital of Yunnan Province, Kunming, China;Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;Department of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;Department of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;College of Medicine, Kunming University of Science and Technology, Department of Ultrasound, The First People’s Hospital of Yunnan Province, Kunming, China;

关键词: Breast Imaging Reporting and Data System;    magnetic resonance imaging;    ultrasound;    breast tumor;    mammography;   

DOI  :  10.3389/fonc.2022.807402

 received in 2021-11-02, accepted in 2022-01-03,  发布年份 2022

来源: Frontiers

【 摘 要 】

ObjectivesTo downgrade BI-RADS 4A patients by constructing a nomogram using R software.Materials and MethodsA total of 1,717 patients were retrospectively analyzed who underwent preoperative ultrasound, mammography, and magnetic resonance examinations in our hospital from August 2019 to September 2020, and a total of 458 patients of category BI-RADS 4A (mean age, 47 years; range 18–84 years; all women) were included. Multivariable logistic regression was used to screen out the independent influencing parameters that affect the benign and malignant tumors, and the nomogram was constructed by R language to downgrade BI-RADS 4A patients to eligible category.ResultsOf 458 BI-RADS 4A patients, 273 (59.6%) were degraded to category 3. The malignancy rate of these 273 lesions is 1.5% (4/273) (<2%), and the sensitivity reduced to 99.6%, the specificity increased from 4.41% to 45.3%, and the accuracy increased from 63.4% to 78.8%.ConclusionBy constructing a nomogram, some patients can be downgraded to avoid unnecessary biopsy.

【 授权许可】

Unknown   
Copyright © 2022 Xie, Zhu, Chai, Zong, Xu, Zhan and Zhang