The association between diet quality index-international and inflammatory markers in Iranian overweight and obese women

Frontiers in Nutrition

Nutrition

Farideh Shiraseb¹  Khadijeh Mirzaei²  Reza Bagheri³  Alexei Wong⁴  Stacey Alvarez-Alvarado⁵  Sahar Noori⁶  Sara Ebrahimi⁷ 

[1] Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran;Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran;Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran;Department of Exercise Physiology, University of Isfahan, Isfahan, Iran;Department of Health and Human Performance, Marymount University, Arlington, VA, United States;Department of Neurology, College of Medicine- Jacksonville, University of Florida, Jacksonville, FL, United States;Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran;The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC, Australia;

关键词: inflammatory markers;    obese;    overweight;    women;    diet quality index-international (DQI-I);   

DOI  :  10.3389/fnut.2023.1164281

 received in 2023-02-12, accepted in 2023-04-26,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectivesThe present study was conducted to evaluate whether there is a link between the diet quality index (DQI) and markers of systemic inflammation in Iranian overweight and obese women.MethodsThis cross-sectional study included 200 Iranian overweight and obese women aged 18–48 years. The DQI-international (DQI-I) comprises four main components: variety, adequacy, moderation, and overall balance. Blood samples were collected in a fasted state to measure inflammatory markers.ResultsAfter adjusting for age, body mass index (BMI), physical activity, total energy intake, economic status, education, supplement intake, age of starting obesity, and history of body mass loss, a marginally significant negative association was observed between the homeostasis model assessment of insulin resistance (HOMA–IR) and the DQI–I (β: −0.015, 95% CI: −0.03, 0.000; p = 0.061). The results after adjustment showed that DQI–I has a negative association with high-sensitivity C-reactive protein (hs–CRP) concentrations (β: −0.031, 95% CI: −0.104, −0.031; p = 0.023). Furthermore, negative associations were observed between the adequacy component and levels of HOMA–IR (β: −0.025, 95% CI: −0.100, 0.047, p = 0.050) and hs-CRP (β: −0.615, 95% CI: −1.191, −0.020; p = 0.045). In addition, negative associations were found between transforming growth factor-β (TGF-β) and balance score (β: −6.270, 95% CI: −39.211, −3.661, p = 0.020), as well as HOMA–IR (β: −0.080, 95% CI: −0.202, −0.000, p = 0.041) and chemoattractant protein−1 (MCP−1) (β: −0.562, 95% CI: −11.414, −0.282, p = 0.021), with the various component. A marginally significant negative association between galectin 3 (Gal-3) and moderation score (β: −0.451, 95% CI: −1.171, 0.060, p = 0.060) was found. In addition, a marginally significant inverse association was also established between hs–CRP and variety score (β: −0.311, 95% CI: −0.970, 0.001, p = 0.052). The Receiver Operating characteristic (ROC) curve analysis demonstrated that DQI–I might better predict HOMA–IR with a cut point of 3.13 (AUC = 0.698, 0.511–0.699, p = 0.050).ConclusionThese findings showed that a higher adherence to diet quality and its components could probably be related to lowering the inflammatory markers considerably in overweight and obese women.

【 授权许可】

Unknown   
Copyright © 2023 Shiraseb, Ebrahimi, Noori, Bagheri, Alvarez-Alvarado, Wong and Mirzaei.