Heterometallic lanthanide complexes with site-specific binding that enable simultaneous visible and NIR-emission

Frontiers in Chemistry

Chemistry

Stephen Faulkner¹  Sam Hay²  Jake Hemsworth³  Louise S. Natrajan³  Matthew E. Thornton³  Patrick Parkinson⁴ 

[1] Department of Chemistry, Chemistry Research Laboratory, The University of Oxford, Oxford, United Kingdom;Department of Chemistry, Faculty of Science and Engineering, Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom;Department of Chemistry, Faculty of Science and Engineering, The University of Manchester, Manchester, United Kingdom;Department of Physics and Astronomy and the Photon Science Institute, Faculty of Science and Engineering, The University of Manchester, Manchester, United Kingdom;

关键词: Lanthanide;    luminescence;    energy transfer;    NIR emission;    Macrocycle;   

DOI  :  10.3389/fchem.2023.1232690

 received in 2023-06-01, accepted in 2023-07-17,  发布年份 2023

来源: Frontiers

【 摘 要 】

Macrocyclic lanthanide complexes have become widely developed due to their distinctive luminescence characteristics and wide range of applications in biological imaging. However, systems with sufficient brightness and metal selectivity can be difficult to produce on a molecular scale. Presented herein is the stepwise introduction of differing lanthanide ions in a bis-DO3A/DTPA scaffold to afford three trinuclear bimetallic [Ln2Ln’] lanthanide complexes with site-specific, controlled binding [(Yb2Tb), (Eu2Tb), (Yb2Eu)]. The complexes display simultaneous emission from all LnIII centers across the visible (TbIII, EuIII) and near infra-red (YbIII) spectrum when excited via phenyl ligand sensitization at a wide range of temperatures and are consequently of interest for exploiting imaging in the near infra-red II biological window. Analysis of lifetime data over a range of excitation regimes reveals intermetallic communication between TbIII and EuIII centers and further develops the understanding of multimetallic lanthanide complexes.

【 授权许可】

Unknown   
Copyright © 2023 Thornton, Hemsworth, Hay, Parkinson, Faulkner and Natrajan.