Seroprevalence of herpes simplex virus type 1 and type 2 among the migrant workers in Qatar

Virology Journal

Research

Duaa W. Al-Sadeq¹  Gheyath K. Nasrallah²  Fathima H. Amanullah²  Hadi M. Yassine²  Asmaa A. Al Thani²  Parveen B. Nizamuddin²  Farah M. Shurrab²  Peter Coyle³  Hanan F. Abdul Rahim⁴  Ashraf Abdelkarim⁵  Odette Chaghoury⁵  Sami Abdeen⁵  Abdullatif Al Khal⁵  Elias Tayar⁵  Jinan Suliman⁵  Anvar Hassan Kaleeckal⁵  Andrew Jeremijenko⁵  Einas Al Kuwari⁵  Mohamed Sahl⁶  Soha R. Dargham⁷  Hiam Chemaitelly⁸  Laith J. Abu-Raddad⁹  Houssein H. Ayoub^1,10  Roberto Bertollini^1,11  Mohamed H. Al-Thani^1,11  Elmoubasher Farag^1,11  Faisal Daraan^1,11  Hamad Eid Al Romaihi^1,11  Ahmed Ismail^1,11  Nahid Mostafa^1,11  Mohamed Ghaith Al Kuwari^1,12  Inayath M. Umar^1,13  Meynard J. A. Agsalog^1,13  Hasan Ali Kasem^1,13  Anas Ansari^1,13  Ahmad Ali Ataalla^1,13  Mohamed Morhaf M. H. Alakshar^1,13  Mohamed M. Thaivalappil^1,13  Abdulsalam Ali A. H. Al-Qahtani^1,13  Feroz J. Poolakundan^1,13  Ayat A. Alkhalaf^1,13  Abubacker S. Thoyalil^1,13  Bassam K. Akkarathodiyil^1,13  Sanjay U. Ranbhise^1,13  Sandeep Chougule^1,13  Abhilash K. K. V. Gopinathan^1,13  Saed M. A. Saefan^1,13  Monther H. A. Al-Shedifat^1,13 

[1] Biomedical Research Center, Qatar University, Doha, Qatar;Biomedical Research Center, Qatar University, Doha, Qatar;Department of Biomedical Science, College of Health Sciences, QU Health, Qatar University, 2713, Doha, Qatar;Biomedical Research Center, Qatar University, Doha, Qatar;Hamad Medical Corporation, Doha, Qatar;Wellcome-Wolfson Institute for Experimental Medicine, Queens University, Belfast, UK;Department of Public Health, College of Health Sciences, QU Health, Qatar University, Doha, Qatar;Hamad Medical Corporation, Doha, Qatar;Hamad Medical Corporation, Doha, Qatar;Ministry of Public Health, Doha, Qatar;Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Doha, Qatar;World Health Organization Collaborating Centre for Disease Epidemiology Analytics On HIV/AIDS, Sexually Transmitted Infections, and Viral Hepatitis, Weill Cornell Medicine–Qatar, Cornell University, Qatar Foundation – Education City, P.O. Box 24144, Doha, Qatar;Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Doha, Qatar;World Health Organization Collaborating Centre for Disease Epidemiology Analytics On HIV/AIDS, Sexually Transmitted Infections, and Viral Hepatitis, Weill Cornell Medicine–Qatar, Cornell University, Qatar Foundation – Education City, P.O. Box 24144, Doha, Qatar;Department of Population Health Sciences, Weill Cornell Medicine, Cornell University, New York, NY, USA;Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Doha, Qatar;World Health Organization Collaborating Centre for Disease Epidemiology Analytics On HIV/AIDS, Sexually Transmitted Infections, and Viral Hepatitis, Weill Cornell Medicine–Qatar, Cornell University, Qatar Foundation – Education City, P.O. Box 24144, Doha, Qatar;Department of Population Health Sciences, Weill Cornell Medicine, Cornell University, New York, NY, USA;Department of Public Health, College of Health Sciences, QU Health, Qatar University, Doha, Qatar;College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar;Mathematics Program, Department of Mathematics, Statistics, and Physics, College of Arts and Sciences, Qatar University, Doha, Qatar;Ministry of Public Health, Doha, Qatar;Primary Health Care Corporation, Doha, Qatar;Qatar Red Crescent Society, Doha, Qatar;

关键词: HSV-1;    HSV-2;    Prevalence;    Genital herpes;    Genital ulcer disease;    Survey;    Cross sectional study;    Migrants;    Qatar;   

DOI  :  10.1186/s12985-023-02157-1

 received in 2023-04-25, accepted in 2023-08-10,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundLimited data exists on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections in migrant populations. This study investigated HSV-1 and HSV-2 seroprevalences and associations among craft and manual workers (CMWs) in Qatar who constitute 60% of Qatar’s population.MethodsA national population-based cross-sectional seroprevalence survey was conducted on the CMW population, all men, between July 26 and September 9, 2020. 2,612 sera were tested for anti-HSV-1 IgG antibodies using HerpeSelect 1 ELISA IgG kits and for anti-HSV-2 IgG antibodies using HerpeSelect 2 ELISA IgG kits (Focus Diagnostics, USA). Univariable and multivariable logistic regression analyses were conducted to identify associations with HSV-1 and HSV-2 infections.ResultsSerological testing identified 2,171 sera as positive, 403 as negative, and 38 as equivocal for HSV-1 antibodies, and 300 sera as positive, 2,250 as negative, and 62 as equivocal for HSV-2 antibodies. HSV-1 and HSV-2 seroprevalences among CMWs were estimated at 84.2% (95% CI 82.8–85.6%) and 11.4% (95% CI 10.1–12.6%), respectively. HSV-1 infection was associated with nationality, educational attainment, and occupation. HSV-2 infection was associated with age, nationality, and educational attainment.ConclusionsOver 80% of CMWs are infected with HSV-1 and over 10% are infected with HSV-2. The findings highlight the need for sexual health programs to tackle sexually transmitted infections among the CMW population.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

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Fig. 4