期刊论文详细信息
World Journal of Surgical Oncology | |
The optimal surgery timing after stenting in colorectal cancer patients with malignant obstruction: additionally compared with emergency surgery | |
Research | |
Dong Kyung Chang1  Eun Ran Kim1  Sung Noh Hong1  Ji Eun Kim1  Young Ho Kim1  Ji Eun Na2  | |
[1]Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, 06351, Seoul, Korea | |
[2]Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, 06351, Seoul, Korea | |
[3]Department of Medicine, Inje University Haeundae Paik Hospital, Busan, Korea | |
关键词: Colorectal cancer; Malignant obstruction; Self-expandable metal stent; Optimal timing of surgery; | |
DOI : 10.1186/s12957-023-03130-6 | |
received in 2023-06-18, accepted in 2023-07-29, 发布年份 2023 | |
来源: Springer | |
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【 摘 要 】
BackgroundThis study aimed to determine short-term and long-term outcomes according to time intervals after stenting and compared them with those of emergency surgery (ES) in colorectal cancer (CRC) with malignant obstruction.MethodsCRC with malignant obstructions was reviewed retrospectively between January 2008 and July 2018. Of a total of 539 patients who visited the emergency room and underwent ES, 133 were enrolled in the ES group. Of a total of 567 patients who initially received stenting and subsequently underwent elective surgery, 220 were enrolled in the SEMS group. The interval between SEMS placement and elective surgery was classified as < 11 days, 11–17 days, and > 17 days.ResultsFor those who received SEMS (n = 220), those with a time interval of 11–17 days (n = 97) had fewer hospital days than those with a time interval of < 11 days (n = 68) (8 days vs. 15 days) and less stoma formation than those with a time interval of > 17 days (n = 55) (1.0% vs. 14.6%). Multivariable analysis revealed a decreased risk of death for the group with a time interval of 11–17 days (20.6%) compared to the ES group (31.6%) (hazard ratio: 0.48; 95% confidence interval: 0.24–0.97). Disease-free survival was comparable between the SEMS and ES groups regardless of the time interval (log-rank p = 0.52).ConclusionsThe time interval of 11–17 days after stenting to elective surgery appeared to be associated with the most favorable outcomes.【 授权许可】
CC BY
© BioMed Central Ltd., part of Springer Nature 2023
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