High excess-free-fructose beverage consumption is not associated with prevalent allergy in US adults: a population-based analysis of NHANES 2005–2006

Journal of Health, Population and Nutrition

Research

Ruili Yu¹  Bo Yang²  Lili Cai³ 

[1] Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, 100038, Beijing, China;Department of Hematology, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, 28 Fuxing Road, 100853, Beijing, China;Department of Laboratory Medicine, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, 28 Fuxing Road, 100853, Beijing, China;

关键词: Allergic sensitization;    Allergic symptoms;    High excess-free-fructose (EFF) beverage;    High-fructose corn syrup (HFCS);    National Health and Nutrition Examination Survey (NHANES);   

DOI  :  10.1186/s41043-023-00439-6

 received in 2023-06-14, accepted in 2023-08-25,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundA strong association exists between high-excess free fructose (EFF) beverage consumption and prevalent allergy in children and adolescents; however, whether this association exists in the adult population is unclear. Therefore, this study aimed to investigate the relationship between high-EFF beverage intake and prevalent allergy.MethodsThis cross-sectional study extracted data from the National Health and Nutrition Examination Survey 2005–2006. Adults aged ≥ 20 were eligible for inclusion, excluding those without complete information on beverage intake, allergic symptom survey, and allergen-specific immunoglobulin E test results. A total of 2077 adults were included. Univariate and multivariable logistic regression analyses determined the associations between high-EFF beverage consumption, prevalent allergic symptoms, and allergic sensitization.ResultsAfter adjusting for confounders, there were no significant associations between high intake (vs. low) of sum of high-EFF beverage (adjusted odds ratio [aOR] = 1.10, 95% confidence interval [CI] 0.77, 1.57), apple juice (aOR = 0.95, 95% 0.55, 1.65), fruit drinks (aOR = 0.95, 95%CI 0.70, 1.29), soft drinks (aOR = 1.17, 95%CI 0.89, 1.55) and presence of allergic sensitization, or allergic symptoms. Stratified analyses also revealed no associations between high intake of high-EFF beverage in sum, presence of allergic symptoms or sensitization among individuals aged 20–39y, 40–59y, and ≥ 60y.ConclusionsOur findings indicate no independent association between frequent intake of high-EFF beverage and increased likelihood of allergy in US adults.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023