Related neural networks underlie suppression of emotion, memory, motor processes as identified by data-driven analysis

BMC Neuroscience

Research Article

Karisa J. Hunt¹  Brendan E. Depue¹  Lindsay K. Knight² 

[1] Department of Psychological and Brain Sciences, University of Louisville, 2301 S, 3rd St., 40292, Louisville, KY, USA;Department of Psychological and Brain Sciences, University of Louisville, 2301 S, 3rd St., 40292, Louisville, KY, USA;Insightec Ltd., Chicago, IL, USA;

关键词: Inhibitory control;    Emotion regulation;    Memory suppression;    Motor inhibition;    Independent component analysis;    Intrinsic connectivity networks;   

DOI  :  10.1186/s12868-023-00812-5

 received in 2022-04-30, accepted in 2023-07-14,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundGoal-directed behavior benefits from self-regulation of cognitive and affective processes, such as emotional reactivity, memory retrieval, and prepotent motor response. Dysfunction in self-regulation is a common characteristic of many psychiatric disorders, such as PTSD and ADHD. This study sought to determine whether common intrinsic connectivity networks (ICNs; e.g. default mode network) are involved in the regulation of emotion, motor, and memory processes, and if a data-driven approach using independent component analysis (ICA) would successfully identify such ICNs that contribute to inhibitory regulation.MethodsEighteen participants underwent neuroimaging while completing an emotion regulation (ER) task, a memory suppression (Think/No-Think; TNT) task, and a motor inhibition (Stop Signal; SS) task. ICA (CONN; MATLAB) was conducted on the neuroimaging data from each task and corresponding components were selected across tasks based on interrelated patterns of activation. Subsequently, ICNs were correlated with behavioral performance variables from each task.ResultsICA indicated a common medial prefrontal network, striatal network, and frontoparietal executive control network, as well as downregulation in task-specific ROIs.ConclusionsThese results illustrate that common ICNs were exhibited across three distinct inhibitory regulation tasks, as successfully identified through a data-driven approach (ICA).

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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