Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study

Journal of Ovarian Research

Research

Wen Yao¹  Jingmin Wang¹  Zhuo Liu¹  Aihua Liu¹  Tingting Zhao¹  Jie Yang¹  Min Li¹  Xinxin Xie² 

[1] Department of Gynaecology, The First Affiliated Hospital of Anhui Medical University, No.120 Wan Shui Road, Shu Shan District, 230022, Hefei, Anhui Province, China;Department of nursing management, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China;

关键词: Comprehensive unit-based safety program;    Chemotherapy-induced nausea and vomiting;    Ovarian cancer;    Quality of life;    Anxiety;    Depression;   

DOI  :  10.1186/s13048-023-01230-1

 received in 2022-04-24, accepted in 2023-07-07,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundTo explore the effect of intervention programs constructed under the guidance of the comprehensive unit-based safety program (CUSP) model on chemotherapy-induced nausea and vomiting (CINV) in patients with ovarian cancer.MethodAccording to the time of admission, 90 ovarian cancer chemotherapy patients in the first affiliated Hospital of Anhui Medical University from June 2019 to September 2020 were divided into an intervention group and a control group with 45 cases each. Both groups of patients received routine intervention, and the intervention group implemented the CUSP program on this basis. The intervention lasted 8 months. Before and after the intervention, the patients in the ward were used the Multinational Association of Supportive Care in Cancer (MASCC) Antiemesis Tool, the Functional Living Index-Emesis (FLIE), and the Hospital Anxiety and Depression Scale (HADS) for the effect evaluation.ResultsAfter the intervention, the degree of nausea and vomiting frequency in the intervention group were significantly lower than that in the control group, especially the degree of nausea in the delayed phase (P < 0.05). The score of the functional living index-emesis in the intervention group was significantly higher than that in the control group (P < 0.05), and the anxiety and depression in the intervention group were significantly relieved compared to the control group (P < 0.05).ConclusionThe intervention program guided by the CUSP model can significantly alleviate patients’ nausea and vomiting, improve the quality of life, and relieve anxiety and depression. The CUSP model is suitable for clinical practice and has guiding significance for clinical work.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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