Incidence of postoperative administration of opioids in dogs undergoing a tibial plateau leveling osteotomy after intra-operative liposomal bupivacaine administration with or without morphine epidural

BMC Veterinary Research

Research

Jacqueline Carver¹  Jessie Scaglione¹ 

[1]Surgery Department, The Veterinary Medical Center of Long Island, 75 Sunrise Highway, West Islip, NY, USA

关键词: TPLO;    Nocita;    Epidural;   

DOI  :  10.1186/s12917-023-03664-7

 received in 2022-12-05, accepted in 2023-07-18,  发布年份 2023

来源: Springer

【 摘 要 】

ObjectiveTo determine the influence of two intraoperative pain management protocols on the need for additional opioids in patients receiving an epidural and periarticular liposomal bupivacaine (PLB) vs. PLB alone in the 12–24 h period after undergoing a TPLO.Study designRetrospective study.AnimalsOne hundred seventy-four dogs with cranial cruciate ligament tears presenting for TPLO.MethodsMedical records of dogs presenting for a unilateral or bilateral cranial cruciate ligament tear who had a TPLO performed were reviewed for signalment, weight, body condition score, and peri-operative pain management protocol. Dogs were divided into two groups: those who received an epidural and PLB, and those who received only PLB. Post-operative opioid administration was recorded for each group.ResultsPatients who received an epidural and PLB received fewer postoperative opioids. There were 36% fewer opioid injections administered to dogs who received epidurals compared to dogs who did not receive epidurals (IRR) (95% CI) = 0.64 (0.45–0.92), P = 0.02). BCS was not a significant predictor of the post-operative opioid requirement (IRR (95% CI) = 1.3 (0.75–2.4), P = 0.38). When adjusting for BCS as a possible confounder, there were 39% fewer opioid injections in dogs who received epidurals than dogs without (IRR (95% CI) = 0.61 (0.42–0.88), P = 0.009).ConclusionsThe incidence of postoperative opioid administration was significantly diminished in patients receiving both an epidural and PLB.Clinical significanceAdministration of an epidural in addition to infiltration of PLB significantly decreased the incidence of postoperative opioid administration in dogs undergoing a TPLO.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

Fig. 3

Fig. 1