Investigation and analysis of porcine epidemic diarrhea cases and evaluation of different immunization strategies in the large-scale swine farming system

Porcine Health Management

Research

Ligen Yu¹  Xiaoli Guo¹  Yuntong Shi²  Weisheng Wu²  Zheng Yan²  Xiaoyang Zhang²  Zewei Wang²  Lili Wu²  Shouyue Zhu²  Junxian Li²  Yang Li²  Shuangxi Li²  Yongquan Wang²  Bingzhou Zhang²  Jie Qing²  Xiaowen Li²  Zhong Yan³  Xiaofang Hu³  Jing Chen³ 

[1] Research Center of Information Technology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China;Shandong New Hope Liuhe Agriculture and Animal Husbandry Technology Co., Ltd. (NHLH Academy of Swine Research), 253034, Dezhou, China;Xiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd, 253200, Dezhou, China;China Agriculture Research System-Yangling Comprehensive test Station, 712100, Xianyang, China;Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Qingdao, China;Shandong New Hope Liuhe Agriculture and Animal Husbandry Technology Co., Ltd. (NHLH Academy of Swine Research), 253034, Dezhou, China;Xiajin New Hope Liuhe Agriculture and Animal Husbandry Co., Ltd, 253200, Dezhou, China;Shandong Engineering Laboratory of Pig and Poultry Healthy Breeding and Disease Diagnosis Technology, Qingdao, China;

关键词: PEDV;    Prevalence;    Immunization strategy;    The duration of PED epidemic;    Economic evaluation model;   

DOI  :  10.1186/s40813-023-00331-z

 received in 2023-05-30, accepted in 2023-06-30,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundPorcine epidemic diarrhea (PED) is a contagious intestinal disease caused by porcine epidemic diarrhea virus (PEDV) characterized by vomiting, diarrhea, anorexia, and dehydration, which has caused huge economic losses around the world. However, it is very hard to find completely valid approaches to control the transmission of PEDV. At present, vaccine immunity remains the most effective method. To better control the spread of PED and evaluate the validity of different immunization strategies, 240 PED outbreak cases from 577 swine breeding farms were collected and analyzed. The objective of the present study was to analyze the epidemic regularity of PEDV and evaluate two kinds of different immunization strategies for controlling PED.ResultsThe results showed that the main reasons which led to the outbreak of PED were the movement of pig herds between different pig farms (41.7%) and delaying piglets from the normal production flow (15.8%). The prevalence of PEDV in the hot season (May to October) was obviously higher than that in the cold season (January to April, November to December). Results of different vaccine immunity cases showed that immunization with the highly virulent live vaccine (NH-TA2020 strain) and the commercial inactivated vaccine could significantly decrease the frequency of swine breeding farms (5.9%), the duration of PED epidemic (1.70 weeks), and the week batches of dead piglets (0.48 weeks weaned piglets), compared with immunization with commercial attenuated vaccines and inactivated vaccine of PED. Meanwhile, immunization with the highly virulent live vaccine and the commercial inactivated vaccine could bring us more cash flows of Y̶275,274 per year than immunization with commercial live attenuated vaccine and inactivated vaccine in one 3000 sow pig farm within one year.ConclusionTherefore, immunization with highly virulent live vaccine and inactivated vaccine of PED is more effective and economical in the prevention and control of PED in the large-scale swine farming system.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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