Education and clinical pharmacist-led management strategies for the risk and prophylaxis of venous thromboembolism in general surgery

Thrombosis Journal

Research

Nadir Yalçın¹  Zeynep Karaburç Kiracı¹  Kutay Demirkan¹  Ömer Cennet²  Kaya Yorgancı² 

[1] Department of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, 06230, Ankara, Türkiye;Department of General Surgery, Faculty of Medicine, Hacettepe University, 06230, Ankara, Türkiye;

关键词: Venous thromboembolism;    Prophylaxis;    Thromboprophylaxis;    Clinical pharmacist;    General surgery;   

DOI  :  10.1186/s12959-023-00530-2

 received in 2023-05-24, accepted in 2023-08-07,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundDespite the risks of venous thromboembolism (VTE) in surgical patients are well defined, primary thromboprophylaxis (TP) can be neglected. The aim of this study was to evaluate the risk of VTE and appropriateness of TP and to assess the effects of education and clinical pharmacy (CP) services.MethodsThis study was conducted in a total of 3 periods (n = 800): pre-education (n = 340), post-education (n = 269) and CP intervention period (n = 191) and the risk of VTE and the appropriateness of TP were evaluated. At the end of pre-education period, patients were re-evaluated after education was given about the guidelines on TP and an educative poster was posted in the services (post-education period). During the CP intervention period, the CP made recommendations in terms of optimal TP use to the physicians in charge.ResultsWhile there was no significant difference in the optimal TP rate administered to the patients before and after education (138/340, 40.6% vs. 122/269, 45.4%; p = 0.238); this rate was increased to 113/191 (59.2%) in the CP intervention period (p = 0.004). High-risk patients who received one type of TP constituted the majority of patients who did not receive optimal TP. While the ratio of high-risk patients undergoing a single type of TP in the pre- and post-education periods (104/340, 30.6% vs. 83/269, 30.9%), was similar (p = 0.819); with the CP interventions, this rate was reduced to 35/191 (18.3%) (p = 0.001).ConclusionEven though education has positive influence on surgeons, the implementation of CP practices is more effective especially in terms of maintaining optimal TP.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

Fig. 4