Bladder carcinosarcoma treated by cystectomy and adjuvant chemotherapy with good outcomes: a case report

Journal of Medical Case Reports

Case Report

Youssef Omor¹  Mohammed Afif²  Meriem Chihabeddine³  Zineb Dahbi³  Fadila Kouhen³  Nadia Errafiy⁴  Amal Elhossini⁵  Kenza Oqbani⁶ 

[1] Department of Radiology, National Institute of Oncology, Rabat, Morocco;Department of Radiotherapy, Faculty of Medicine of Tangier, Abdelmalek Essaadi University, Tangier, Morocco;Department of Radiotherapy, International University Hospital Sheikh Khalifa, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco;National Reference Laboratory (LNR), Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco;Pathology Laboratory PATHONORD, Tangier, Morocco;Pathology Laboratory, International University Hospital Sheikh Khalifa, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco;

关键词: Bladder carcinosarcoma;    Cystectomy;    Chemotherapy;    Outcomes;   

DOI  :  10.1186/s13256-023-04028-3

 received in 2021-10-23, accepted in 2023-06-06,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundPrimary carcinosarcoma of the bladder is a rare and highly aggressive tumor, representing less than 1% of all bladder neoplasms. There is no specific treatment guideline has for carcinosarcoma of the bladder, and majority of published patients was treated exclusively by surgery.Case presentationWe report a case of 65-year-old Moroccan man, presented with macroscopic hematuria, pollakiuria and painful urination. Histological analysis showed a biphasic epithelial and mesenchymal proliferation, with invasion of lamina propria and muscularis, compatible with diagnosis of bladder carcinosarcoma. The patient was treated with cystectomy and adjuvant chemotherapy based on gemcitabin-cisplatin, 18 months after treatment, patient still free of recurrence.ConclusionCarcinosarcoma of the urinary bladder is a rare and aggressive tumor regardless treatment. A multidisciplinary management based on radical cystectomy and combined adjuvant treatments can improve prognosis. In this work, we suggest to propose adjuvant chemotherapy whenever possible.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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