Triglyceride glucose-body mass index and hypertension risk in iranian adults: a population-based study

BMC Endocrine Disorders

Research

Ebrahim Shakiba¹  Farid Najafi²  Mitra Darbandi²  Yahya Pasdar²  Jafar Navabi³  Hamid Reza Nikbakht⁴ 

[1] Behavioral Disease Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran;Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran;School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran;School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran;

关键词: Insulin resistance;    Hypertension;    Body mass index;    Triglyceride;    Glucose;   

DOI  :  10.1186/s12902-023-01411-5

 received in 2023-06-02, accepted in 2023-07-11,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundInsulin resistance (IR) and obesity are risk factors for hypertension; triglyceride-glucose (TyG) is known as a surrogate for IR. The present study investigated the association between the triglyceride-glucose body mass index (TyG-BMI) index and the risk of hypertension in Iranian adults.MethodsThis study was conducted on a sample of 8,610 participants from the baseline phase of the Ravansar non- communicable diseases (RaNCD) in Iran. A logistic regression model was used to evaluate the relationship between TyG-BMI and hypertension. Receiver operating characteristic (ROC) curve analysis was conducted to estimate the predictive power of TyG-BMI for hypertension.ResultsA total of 4176 men and 4434 women with an average age of 46.74 years were examined. The anthropometric indices were significantly higher in hypertensive than normotensive subjects (P < 0.001). The level of physical activity was significantly higher in the bottom quartiles (P < 0.001). The odds of hypertension in the highest quartile and 3.10 (95% CI: 2.28, 4.16) times significantly higher than the bottom quartile of the TyG-BMI index. The discriminating ability of TyG-BMI to predict blood pressure was 61% (AUC: 0.61; 95% CI: 0.57, 0.63), and higher than BMI and TyG.ConclusionThe TyG-BMI index is associated with an increase in the odds of hypertension. Therefore, the TyG-BMI index can be a new clinical index for early diagnosis of hypertension. Lifestyle modifications such as weight control through physical activity and a healthy diet can help improve IR and prevent hypertension.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

Fig. 4

Fig. 1

40517_2023_261_Article_IEq43.gif