Sleep quality and clinical association with sleep disturbance in systemic sclerosis

BMC Rheumatology

Research

Chingching Foocharoen¹  Ajanee Mahakkanukrauh¹  Siraphop Suwannaroj¹  Nonthaphorn Wongthawa¹  Apichart So-gnern² 

[1] Division of Rheumatology, Department of Medicine, Faculty of Medicine, Khon Kaen University, 40002, Khon Kaen, Thailand;Division of Sleep Medicine, Department of Medicine, Faculty of Medicine, Khon Kaen University, 40002, Khon Kaen, Thailand;

关键词: Systemic sclerosis;    Scleroderma;    Sleep quality;    Sleep disturbance;    Pittsburgh Sleep Quality Index;    Depression;   

DOI  :  10.1186/s41927-023-00346-7

 received in 2022-11-01, accepted in 2023-07-14,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundPoor sleep quality is a common and potentially debilitating problem in systemic sclerosis (SSc). To date, no data clarifies the potential factors related to poor sleep quality and the clinical associations with sleep disturbance among Thais with SSc—mainly the diffuse cutaneous SSc (dcSSc) subset. We aimed to evaluate sleep quality and identify the clinical association with sleep disturbance among SSc patients.MethodsA cross-sectional study was conducted between May 2021 and September 2021. Adult SSc patients were enrolled at the Scleroderma Clinic, Khon Kaen University, Thailand. All patients had their neck circumference measured, underwent airway evaluation using the Mallampati classification, had sleep quality assessed using the Pittsburgh Sleep Quality Index (PSQI), and the Berlin and Patient Health Questionnaire-9 completed. In addition, the clinical association with poor sleep quality (or sleep disturbance) was investigated using the PSQI.ResultsA total of 88 patients were enrolled. Forty-eight (54.6%) patients experienced poor sleep quality (95%CI 43.6–65.2). Digital ulcers and dyspepsia were associated with poor sleep quality as per a logistic regression (OR 10.73: 95%CI 1.09–106.15 and 4.60: 95%CI 1.01–20.89), respectively. Overall pain—evaluated using the visual analog scale (VAS)—was positively correlated with the PSQI score (Rho 0.2586; p = 0.02).ConclusionAround half of the SSc patients reported poor sleep quality, and the significantly associated factors were digital ulcers and dyspepsia. The PSQI scores positively correlated with overall pain as evaluated by VAS. With early assessment and treatment of digital ulcers, stomach symptoms, and pain control, sleep problems might be reduced among SSc patients.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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